TY - JOUR
T1 - Emergency surgery for acute diverticulitis
T2 - Which operation? A national surgical quality improvement program study
AU - Tadlock, Mathew D.
AU - Karamanos, Efstathios
AU - Skiada, Dimitra
AU - Inaba, Kenji
AU - Talving, Peep
AU - Senagore, Anthony
AU - Demetriades, Demetrios
PY - 2013/6
Y1 - 2013/6
N2 - BACKGROUND: The optimal surgical management of acute diverticulitis is still a controversial and unresolved issue. While the Hartmann's procedure (') is the most commonly performed operation, primary anastomosis (PA), with or without proximal diversion, has also been used with increasing frequency. METHODS: This is a National Surgical Quality Improvement Program database study including all patients requiring emergency surgery for acute diverticulitis. Three operative approaches were analyzed: HP, colectomy with PA, and colectomy with PA with proximal diversion (PAPD). Mortality and postoperative outcomes were compared between the three groups using a logistical regression model. RESULTS: There were 1,314 patients who required emergent operation for acute diverticulitis, 75.4% underwent HP, 21.7% underwent PA, and 2.9% underwent PAPD. Thirty-day mortality was 7.3%, 4.6%, and 1.6% for HP, PA, and PAPD respectively ( p = 0.163), while surgical site infections occurred in 19.7%, 17.9%, and 13.2%, respectively ( p = 0.59). After multivariable analysis adjusting for age, alcohol consumption, comorbidities, steroid use, preoperative laboratory values, hemorrhage at admission and laparoscopic surgery, the adjusted odds ratio for 30-day mortality comparing PA with HP was 0.77 (95% confidence interval [CI], 0.38Y1.56; p = 0.465), 0.47 (95% CI, 0.06Y3.74; p = 0.479) comparing PAPD with HP, and 1.62 (95% CI, 0.19Y13.78; p = 0.658) comparing PAwith PAPD. In addition, the three groups did not have significantly different adjusted odds ratio for the development of surgical infectious complications, acute kidney injury, cardiovascular incidents, or venous thromboembolism after surgery. CONCLUSION: Resection and PA in patients undergoing an emergency operation for acute diverticulitis is a safe alternative to the HP, with no significant difference in mortality or postoperative surgical site infections.LEVEL OF EVIDENCE: Therapeutic study, level IV.
AB - BACKGROUND: The optimal surgical management of acute diverticulitis is still a controversial and unresolved issue. While the Hartmann's procedure (') is the most commonly performed operation, primary anastomosis (PA), with or without proximal diversion, has also been used with increasing frequency. METHODS: This is a National Surgical Quality Improvement Program database study including all patients requiring emergency surgery for acute diverticulitis. Three operative approaches were analyzed: HP, colectomy with PA, and colectomy with PA with proximal diversion (PAPD). Mortality and postoperative outcomes were compared between the three groups using a logistical regression model. RESULTS: There were 1,314 patients who required emergent operation for acute diverticulitis, 75.4% underwent HP, 21.7% underwent PA, and 2.9% underwent PAPD. Thirty-day mortality was 7.3%, 4.6%, and 1.6% for HP, PA, and PAPD respectively ( p = 0.163), while surgical site infections occurred in 19.7%, 17.9%, and 13.2%, respectively ( p = 0.59). After multivariable analysis adjusting for age, alcohol consumption, comorbidities, steroid use, preoperative laboratory values, hemorrhage at admission and laparoscopic surgery, the adjusted odds ratio for 30-day mortality comparing PA with HP was 0.77 (95% confidence interval [CI], 0.38Y1.56; p = 0.465), 0.47 (95% CI, 0.06Y3.74; p = 0.479) comparing PAPD with HP, and 1.62 (95% CI, 0.19Y13.78; p = 0.658) comparing PAwith PAPD. In addition, the three groups did not have significantly different adjusted odds ratio for the development of surgical infectious complications, acute kidney injury, cardiovascular incidents, or venous thromboembolism after surgery. CONCLUSION: Resection and PA in patients undergoing an emergency operation for acute diverticulitis is a safe alternative to the HP, with no significant difference in mortality or postoperative surgical site infections.LEVEL OF EVIDENCE: Therapeutic study, level IV.
KW - Acute diverticulitis
KW - Hartmann's procedure
KW - Primary anastomosis
KW - Proximal diversion
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U2 - 10.1097/TA.0b013e3182924a82
DO - 10.1097/TA.0b013e3182924a82
M3 - Article
C2 - 23694862
AN - SCOPUS:84880085486
SN - 2163-0755
VL - 74
SP - 1385
EP - 1391
JO - Journal of Trauma and Acute Care Surgery
JF - Journal of Trauma and Acute Care Surgery
IS - 6
ER -