Emerging bacterial zoonotic and vector-borne diseases

Ecological and epidemiological factors

David Walker, Alan G. Barbour, James H. Oliver, Robert S. Lane, J. Stephen Dumler, David T. Dennis, David H. Persing, Abdu F. Azad, Edward McSweegan

Research output: Contribution to journalArticle

98 Citations (Scopus)

Abstract

Among the etiologic agents of emerging infectious diseases are several bacterial organisms that naturally reside in animal and arthropod hosts. The most compelling emerging bacterial zoonotic and vector-borne diseases in the United States are Lyme disease; a Southern erythema migrans-like illness; human monocytic ehrlichiosis; human granulocytic ehrlichiosis; a novel cat flea-associated typhus group rickettsiosis; bartonelloses of immunocompetent and immunocompromised persons, particularly with AIDS; and sylvatic plague. Some of these antimicrobial-treatable infections are life threatening. During the acute stage of illness when antimicrobial agents are most effective, the flulike clinical signs and symptoms and available laboratory tests frequently do not point to a particular diagnosis. Epidemiological factors determined by the ecology of the bacteria are often the most useful diagnostic clues. The recognition of these evolving problems emphasizes the need for development of better laboratory diagnostic methods, for surveillance for and tracking of disease, and for continued research into factors contributing to transmission of the organisms. The continual appearance of previously unidentified bacterial infections requires prospective national strategies for timely recognition of the syndrome, identification of the agent, establishment of criteria and methods for diagnosis, optimization of the treatment regimen, and determination of successful approaches to prevention and control.

Original languageEnglish (US)
Pages (from-to)463-469
Number of pages7
JournalJournal of the American Medical Association
Volume275
Issue number6
DOIs
StatePublished - Feb 14 1996

Fingerprint

Ehrlichiosis
Disease Vectors
Zoonoses
Ctenocephalides
Bartonella Infections
Emerging Communicable Diseases
Epidemic Louse-Borne Typhus
Plague
Lyme Disease
Arthropods
Erythema
Anti-Infective Agents
Ecology
Bacterial Infections
Signs and Symptoms
Acquired Immunodeficiency Syndrome
Bacteria
Infection
Research
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Walker, D., Barbour, A. G., Oliver, J. H., Lane, R. S., Dumler, J. S., Dennis, D. T., ... McSweegan, E. (1996). Emerging bacterial zoonotic and vector-borne diseases: Ecological and epidemiological factors. Journal of the American Medical Association, 275(6), 463-469. https://doi.org/10.1001/jama.275.6.463

Emerging bacterial zoonotic and vector-borne diseases : Ecological and epidemiological factors. / Walker, David; Barbour, Alan G.; Oliver, James H.; Lane, Robert S.; Dumler, J. Stephen; Dennis, David T.; Persing, David H.; Azad, Abdu F.; McSweegan, Edward.

In: Journal of the American Medical Association, Vol. 275, No. 6, 14.02.1996, p. 463-469.

Research output: Contribution to journalArticle

Walker, D, Barbour, AG, Oliver, JH, Lane, RS, Dumler, JS, Dennis, DT, Persing, DH, Azad, AF & McSweegan, E 1996, 'Emerging bacterial zoonotic and vector-borne diseases: Ecological and epidemiological factors', Journal of the American Medical Association, vol. 275, no. 6, pp. 463-469. https://doi.org/10.1001/jama.275.6.463
Walker, David ; Barbour, Alan G. ; Oliver, James H. ; Lane, Robert S. ; Dumler, J. Stephen ; Dennis, David T. ; Persing, David H. ; Azad, Abdu F. ; McSweegan, Edward. / Emerging bacterial zoonotic and vector-borne diseases : Ecological and epidemiological factors. In: Journal of the American Medical Association. 1996 ; Vol. 275, No. 6. pp. 463-469.
@article{ed6e84e1e1be4e079118bce56ba9c661,
title = "Emerging bacterial zoonotic and vector-borne diseases: Ecological and epidemiological factors",
abstract = "Among the etiologic agents of emerging infectious diseases are several bacterial organisms that naturally reside in animal and arthropod hosts. The most compelling emerging bacterial zoonotic and vector-borne diseases in the United States are Lyme disease; a Southern erythema migrans-like illness; human monocytic ehrlichiosis; human granulocytic ehrlichiosis; a novel cat flea-associated typhus group rickettsiosis; bartonelloses of immunocompetent and immunocompromised persons, particularly with AIDS; and sylvatic plague. Some of these antimicrobial-treatable infections are life threatening. During the acute stage of illness when antimicrobial agents are most effective, the flulike clinical signs and symptoms and available laboratory tests frequently do not point to a particular diagnosis. Epidemiological factors determined by the ecology of the bacteria are often the most useful diagnostic clues. The recognition of these evolving problems emphasizes the need for development of better laboratory diagnostic methods, for surveillance for and tracking of disease, and for continued research into factors contributing to transmission of the organisms. The continual appearance of previously unidentified bacterial infections requires prospective national strategies for timely recognition of the syndrome, identification of the agent, establishment of criteria and methods for diagnosis, optimization of the treatment regimen, and determination of successful approaches to prevention and control.",
author = "David Walker and Barbour, {Alan G.} and Oliver, {James H.} and Lane, {Robert S.} and Dumler, {J. Stephen} and Dennis, {David T.} and Persing, {David H.} and Azad, {Abdu F.} and Edward McSweegan",
year = "1996",
month = "2",
day = "14",
doi = "10.1001/jama.275.6.463",
language = "English (US)",
volume = "275",
pages = "463--469",
journal = "JAMA - Journal of the American Medical Association",
issn = "0002-9955",
publisher = "American Medical Association",
number = "6",

}

TY - JOUR

T1 - Emerging bacterial zoonotic and vector-borne diseases

T2 - Ecological and epidemiological factors

AU - Walker, David

AU - Barbour, Alan G.

AU - Oliver, James H.

AU - Lane, Robert S.

AU - Dumler, J. Stephen

AU - Dennis, David T.

AU - Persing, David H.

AU - Azad, Abdu F.

AU - McSweegan, Edward

PY - 1996/2/14

Y1 - 1996/2/14

N2 - Among the etiologic agents of emerging infectious diseases are several bacterial organisms that naturally reside in animal and arthropod hosts. The most compelling emerging bacterial zoonotic and vector-borne diseases in the United States are Lyme disease; a Southern erythema migrans-like illness; human monocytic ehrlichiosis; human granulocytic ehrlichiosis; a novel cat flea-associated typhus group rickettsiosis; bartonelloses of immunocompetent and immunocompromised persons, particularly with AIDS; and sylvatic plague. Some of these antimicrobial-treatable infections are life threatening. During the acute stage of illness when antimicrobial agents are most effective, the flulike clinical signs and symptoms and available laboratory tests frequently do not point to a particular diagnosis. Epidemiological factors determined by the ecology of the bacteria are often the most useful diagnostic clues. The recognition of these evolving problems emphasizes the need for development of better laboratory diagnostic methods, for surveillance for and tracking of disease, and for continued research into factors contributing to transmission of the organisms. The continual appearance of previously unidentified bacterial infections requires prospective national strategies for timely recognition of the syndrome, identification of the agent, establishment of criteria and methods for diagnosis, optimization of the treatment regimen, and determination of successful approaches to prevention and control.

AB - Among the etiologic agents of emerging infectious diseases are several bacterial organisms that naturally reside in animal and arthropod hosts. The most compelling emerging bacterial zoonotic and vector-borne diseases in the United States are Lyme disease; a Southern erythema migrans-like illness; human monocytic ehrlichiosis; human granulocytic ehrlichiosis; a novel cat flea-associated typhus group rickettsiosis; bartonelloses of immunocompetent and immunocompromised persons, particularly with AIDS; and sylvatic plague. Some of these antimicrobial-treatable infections are life threatening. During the acute stage of illness when antimicrobial agents are most effective, the flulike clinical signs and symptoms and available laboratory tests frequently do not point to a particular diagnosis. Epidemiological factors determined by the ecology of the bacteria are often the most useful diagnostic clues. The recognition of these evolving problems emphasizes the need for development of better laboratory diagnostic methods, for surveillance for and tracking of disease, and for continued research into factors contributing to transmission of the organisms. The continual appearance of previously unidentified bacterial infections requires prospective national strategies for timely recognition of the syndrome, identification of the agent, establishment of criteria and methods for diagnosis, optimization of the treatment regimen, and determination of successful approaches to prevention and control.

UR - http://www.scopus.com/inward/record.url?scp=0030045235&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030045235&partnerID=8YFLogxK

U2 - 10.1001/jama.275.6.463

DO - 10.1001/jama.275.6.463

M3 - Article

VL - 275

SP - 463

EP - 469

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

SN - 0002-9955

IS - 6

ER -