Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage

Sami A. Chadi, Abe Fingerhut, Mariana Berho, Steven R. DeMeester, James W. Fleshman, Neil H. Hyman, David A. Margolin, Joseph E. Martz, Elisabeth C. McLemore, Daniela Molena, Martin I. Newman, Janice F. Rafferty, Bashar Safar, Anthony J. Senagore, Oded Zmora, Steven D. Wexner

    Research output: Contribution to journalArticlepeer-review

    155 Scopus citations

    Abstract

    Anastomotic leaks represent one of the most alarming complications following any gastrointestinal anastomosis due to the substantial effects on post-operative morbidity and mortality of the patient with long-lasting effects on the functional and oncologic outcomes. There is a lack of consensus related to the definition of an anastomotic leak, with a variety of options for prevention and management. A number of patient-related and technical risk factors have been found to be associated with the development of an anastomotic leak and have inspired the development of various preventative measures and technologies. The International Multispecialty Anastomotic Leak Global Improvement Exchange group was convened to establish a consensus on the definition of an anastomotic leak as well as to discuss the various diagnostic, preventative, and management measures currently available.

    Original languageEnglish (US)
    Pages (from-to)2035-2051
    Number of pages17
    JournalJournal of Gastrointestinal Surgery
    Volume20
    Issue number12
    DOIs
    StatePublished - Dec 1 2016

    Keywords

    • Consensus
    • Gastrointestinal anastomotic leakage
    • International Multispecialty Anastomotic Leak Global Improvement Exchange
    • Morbidity
    • Review

    ASJC Scopus subject areas

    • Surgery
    • Gastroenterology

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