Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage

Sami A. Chadi, Abe Fingerhut, Mariana Berho, Steven R. DeMeester, James W. Fleshman, Neil H. Hyman, David A. Margolin, Joseph E. Martz, Elisabeth C. McLemore, Daniela Molena, Martin I. Newman, Janice F. Rafferty, Bashar Safar, Anthony J. Senagore, Oded Zmora, Steven D. Wexner

Research output: Contribution to journalArticle

49 Scopus citations

Abstract

Anastomotic leaks represent one of the most alarming complications following any gastrointestinal anastomosis due to the substantial effects on post-operative morbidity and mortality of the patient with long-lasting effects on the functional and oncologic outcomes. There is a lack of consensus related to the definition of an anastomotic leak, with a variety of options for prevention and management. A number of patient-related and technical risk factors have been found to be associated with the development of an anastomotic leak and have inspired the development of various preventative measures and technologies. The International Multispecialty Anastomotic Leak Global Improvement Exchange group was convened to establish a consensus on the definition of an anastomotic leak as well as to discuss the various diagnostic, preventative, and management measures currently available.

Original languageEnglish (US)
Pages (from-to)1-17
Number of pages17
JournalJournal of Gastrointestinal Surgery
DOIs
StateAccepted/In press - Sep 16 2016
Externally publishedYes

Keywords

  • Consensus
  • Gastrointestinal anastomotic leakage
  • International Multispecialty Anastomotic Leak Global Improvement Exchange
  • Morbidity
  • Review

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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    Chadi, S. A., Fingerhut, A., Berho, M., DeMeester, S. R., Fleshman, J. W., Hyman, N. H., Margolin, D. A., Martz, J. E., McLemore, E. C., Molena, D., Newman, M. I., Rafferty, J. F., Safar, B., Senagore, A. J., Zmora, O., & Wexner, S. D. (Accepted/In press). Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage. Journal of Gastrointestinal Surgery, 1-17. https://doi.org/10.1007/s11605-016-3255-3