Endemic Venezuelan Equine Encephalitis in Northern Peru

Patricia Aguilar, Ivorlyne P. Greene, Lark L. Coffey, Gladys Medina, Abelardo C. Moncayo, Michael Anishchenko, George V. Ludwig, Michael J. Turell, Monica L. O'Guinn, John Lee, Robert B. Tesh, Douglas M. Watts, Kevin L. Russell, Christine Hice, Stephen Yanoviak, Amy C. Morrison, Terry A. Klein, David J. Dohm, Hilda Guzman, Amelia P A Travassos Da Rosa & 5 others Carolina Guevara, Tadeusz Kochel, James Olson, Cesar Cabezas, Scott Weaver

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Since Venezuelan equine encephalitis virus (VEEV) was isolated in Peru in 1942, >70 isolates have been obtained from mosquitoes, humans, and sylvatic mammals primarily in the Amazon region. To investigate genetic relationships among the Peru VEEV isolates and between the Peru isolates and other VEEV strains, a fragment of the PE2 gene was amplified and analyzed by single-stranded conformation polymorphism. Representatives of seven genotypes underwent sequencing and phylogenetic analysis. The results identified four VEE complex lineages that cocirculate in the Amazon region: subtypes ID (Panama and Colombia/Venezuela genotypes), IIIC, and a new, proposed subtype IIID, which was isolated from a febrile human, mosquitoes, and spiny rats. Both ID lineages and the IIID subtype are associated with febrile human illness. Most of the subtype ID isolates belonged to the Panama genotype, but the Colombia/Venezuela genotype, which is phylogenetically related to epizootic strains, also continues to circulate in the Amazon basin.

Original languageEnglish (US)
Pages (from-to)880-888
Number of pages9
JournalEmerging Infectious Diseases
Volume10
Issue number5
StatePublished - May 2004

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Venezuelan Equine Encephalomyelitides
Peru
Venezuelan Equine Encephalitis Viruses
Genotype
Panama
Venezuela
Colombia
Culicidae
Fever
Mammals
Genes

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Aguilar, P., Greene, I. P., Coffey, L. L., Medina, G., Moncayo, A. C., Anishchenko, M., ... Weaver, S. (2004). Endemic Venezuelan Equine Encephalitis in Northern Peru. Emerging Infectious Diseases, 10(5), 880-888.

Endemic Venezuelan Equine Encephalitis in Northern Peru. / Aguilar, Patricia; Greene, Ivorlyne P.; Coffey, Lark L.; Medina, Gladys; Moncayo, Abelardo C.; Anishchenko, Michael; Ludwig, George V.; Turell, Michael J.; O'Guinn, Monica L.; Lee, John; Tesh, Robert B.; Watts, Douglas M.; Russell, Kevin L.; Hice, Christine; Yanoviak, Stephen; Morrison, Amy C.; Klein, Terry A.; Dohm, David J.; Guzman, Hilda; Travassos Da Rosa, Amelia P A; Guevara, Carolina; Kochel, Tadeusz; Olson, James; Cabezas, Cesar; Weaver, Scott.

In: Emerging Infectious Diseases, Vol. 10, No. 5, 05.2004, p. 880-888.

Research output: Contribution to journalArticle

Aguilar, P, Greene, IP, Coffey, LL, Medina, G, Moncayo, AC, Anishchenko, M, Ludwig, GV, Turell, MJ, O'Guinn, ML, Lee, J, Tesh, RB, Watts, DM, Russell, KL, Hice, C, Yanoviak, S, Morrison, AC, Klein, TA, Dohm, DJ, Guzman, H, Travassos Da Rosa, APA, Guevara, C, Kochel, T, Olson, J, Cabezas, C & Weaver, S 2004, 'Endemic Venezuelan Equine Encephalitis in Northern Peru', Emerging Infectious Diseases, vol. 10, no. 5, pp. 880-888.
Aguilar P, Greene IP, Coffey LL, Medina G, Moncayo AC, Anishchenko M et al. Endemic Venezuelan Equine Encephalitis in Northern Peru. Emerging Infectious Diseases. 2004 May;10(5):880-888.
Aguilar, Patricia ; Greene, Ivorlyne P. ; Coffey, Lark L. ; Medina, Gladys ; Moncayo, Abelardo C. ; Anishchenko, Michael ; Ludwig, George V. ; Turell, Michael J. ; O'Guinn, Monica L. ; Lee, John ; Tesh, Robert B. ; Watts, Douglas M. ; Russell, Kevin L. ; Hice, Christine ; Yanoviak, Stephen ; Morrison, Amy C. ; Klein, Terry A. ; Dohm, David J. ; Guzman, Hilda ; Travassos Da Rosa, Amelia P A ; Guevara, Carolina ; Kochel, Tadeusz ; Olson, James ; Cabezas, Cesar ; Weaver, Scott. / Endemic Venezuelan Equine Encephalitis in Northern Peru. In: Emerging Infectious Diseases. 2004 ; Vol. 10, No. 5. pp. 880-888.
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