Endoscopic and Surgical Treatments for Achalasia: Who to Treat and How?

Romulo A. Fajardo, Roman V. Petrov, Charles T. Bakhos, Abbas E. Abbas

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Achalasia is a progressive neurodegenerative disorder characterized by failure of relaxation of the lower esophageal sphincter (LES) and altered motility of the esophagus. The traditional, highly effective, surgical approach to relieve obstruction at the LES includes cardiomyotomy. Fundoplication is added to decrease risk of postoperative reflux. Per oral endoscopic myotomy is a new endoscopic procedure that allows division of the LES via transoral route. It has several advantages including less invasiveness, cosmesis, and tailored approach to the length on the myotomy. However, it is associated with increased rate of post-procedural reflux. Various endoscopic interventions are used to address this problem.

Original languageEnglish (US)
Pages (from-to)481-498
Number of pages18
JournalGastroenterology Clinics of North America
Volume49
Issue number3
DOIs
StatePublished - Sep 2020
Externally publishedYes

Keywords

  • Achalasia
  • Cardiomyotomy
  • Gastroesophageal junction
  • Heller myotomy
  • Peroral endoscopic myotomy

ASJC Scopus subject areas

  • Gastroenterology

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