Endoscopic tissue approximation in clinical practice and the OverStitch device: a narrative review

Claire Miller, Jessica Magarinos, Andrew Akcelik, Charles Bakhos, Abbas Abbas, Roman Petrov

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Objective: The current article describes modern endoscopic technologies that allow for advanced endoscopic tissue approximation and suturing. These technologies include such devices as through the scope and over the scope clips, endoscopic suturing OverStitch device and through the scope suturing X-Tack device. Background: Since the original introduction of the diagnostic endoscopy, progress in the field has been astonishing. Over the past several decades endoscopy has made numerous advancements allowing for a minimally invasive mechanism to treat life threatening conditions such as gastrointestinal (GI) bleeding, full thickness injuries, as well as chronic medical conditions such as morbid obesity and achalasia. Methods: A narrative review of all relevant and available literature on endoscopic tissue approximation devices over the last 15 years ago was conducted. Conclusions: Multiple new devices, including endoscopic clips and endoscopic suturing devices, have been developed for endoscopic tissue approximation that allow advanced endoscopic management of a wide variety of GI tract conditions. It is critical for practicing surgeons to actively participate in the development and use of these new technologies and devices in order to maintain leadership in the field, hone expertise, and to drive innovation. Further research in minimally invasive applications for these devices is needed as they continue to be refined. This article provides a general overview of the devices available and their clinical applications.

Original languageEnglish (US)
Article number21
JournalAnnals of Esophagus
StatePublished - Jun 25 2023
Externally publishedYes


  • Endoscopic tissue approximation
  • OverStitch device
  • X-Tack device
  • endoscopic clips
  • endoscopic suturing

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology


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