Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate

Stefan Seewald, Stefan Groth, Parupudi V.J. Sriram, He Xikun, Thawatchai Akaraviputh, Gerardo Mendoza, Boris Brand, Uwe Seitz, Frank Thonke, Nib Soehendra

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70 Scopus citations

Abstract

Background: Biliary leakage is a problematic complication of hepatobiliary surgery. A novel alternative method is described that can obviate the need for reoperation for refractory biliary fistula. Methods: Nine patients with large biliary leaks unresponsive to endoscopic drainage underwent N-butyl-2-cyanoacrylate glue occlusion at ERCP. Results: In 7 patients, occlusion was successful with prompt control of the fistula in a single session, averting reoperation. In 1 patient there was a partial response and in another the treatment was unsuccessful. No procedure-related complication occurred over a median follow-up of 35 months (range: 1.6-160 months). Conclusion: N-butyl-2-cyanoacrylate glue occlusion is a safe and effective endoscopic method for control of refractory bile leaks that eliminates the need for surgical reintervention.

Original languageEnglish (US)
Pages (from-to)916-919
Number of pages4
JournalGastrointestinal endoscopy
Volume56
Issue number6
DOIs
StatePublished - Dec 2002
Externally publishedYes

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ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

Cite this

Seewald, S., Groth, S., Sriram, P. V. J., Xikun, H., Akaraviputh, T., Mendoza, G., Brand, B., Seitz, U., Thonke, F., & Soehendra, N. (2002). Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate. Gastrointestinal endoscopy, 56(6), 916-919. https://doi.org/10.1016/S0016-5107(02)70375-1