Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate

Stefan Seewald, Stefan Groth, Sreeram Parupudi, He Xikun, Thawatchai Akaraviputh, Gerardo Mendoza, Boris Brand, Uwe Seitz, Frank Thonke, Nib Soehendra

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Background: Biliary leakage is a problematic complication of hepatobiliary surgery. A novel alternative method is described that can obviate the need for reoperation for refractory biliary fistula. Methods: Nine patients with large biliary leaks unresponsive to endoscopic drainage underwent N-butyl-2-cyanoacrylate glue occlusion at ERCP. Results: In 7 patients, occlusion was successful with prompt control of the fistula in a single session, averting reoperation. In 1 patient there was a partial response and in another the treatment was unsuccessful. No procedure-related complication occurred over a median follow-up of 35 months (range: 1.6-160 months). Conclusion: N-butyl-2-cyanoacrylate glue occlusion is a safe and effective endoscopic method for control of refractory bile leaks that eliminates the need for surgical reintervention.

Original languageEnglish (US)
Pages (from-to)916-919
Number of pages4
JournalGastrointestinal Endoscopy
Volume56
Issue number6
DOIs
StatePublished - Dec 2002
Externally publishedYes

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Enbucrilate
Reoperation
Adhesives
Biliary Fistula
Endoscopic Retrograde Cholangiopancreatography
Therapeutics
Bile
Fistula
Drainage

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Seewald, S., Groth, S., Parupudi, S., Xikun, H., Akaraviputh, T., Mendoza, G., ... Soehendra, N. (2002). Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate. Gastrointestinal Endoscopy, 56(6), 916-919. https://doi.org/10.1016/S0016-5107(02)70375-1

Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate. / Seewald, Stefan; Groth, Stefan; Parupudi, Sreeram; Xikun, He; Akaraviputh, Thawatchai; Mendoza, Gerardo; Brand, Boris; Seitz, Uwe; Thonke, Frank; Soehendra, Nib.

In: Gastrointestinal Endoscopy, Vol. 56, No. 6, 12.2002, p. 916-919.

Research output: Contribution to journalArticle

Seewald, S, Groth, S, Parupudi, S, Xikun, H, Akaraviputh, T, Mendoza, G, Brand, B, Seitz, U, Thonke, F & Soehendra, N 2002, 'Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate', Gastrointestinal Endoscopy, vol. 56, no. 6, pp. 916-919. https://doi.org/10.1016/S0016-5107(02)70375-1
Seewald, Stefan ; Groth, Stefan ; Parupudi, Sreeram ; Xikun, He ; Akaraviputh, Thawatchai ; Mendoza, Gerardo ; Brand, Boris ; Seitz, Uwe ; Thonke, Frank ; Soehendra, Nib. / Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate. In: Gastrointestinal Endoscopy. 2002 ; Vol. 56, No. 6. pp. 916-919.
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AU - Mendoza, Gerardo

AU - Brand, Boris

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