TY - JOUR
T1 - Endovascular surgical neuro-oncology
T2 - advancing a new subspecialty
AU - Young, Christopher C.
AU - Kan, Peter
AU - Chen, Stephen R.
AU - Lang, Frederick F.
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.
PY - 2024/10
Y1 - 2024/10
N2 - Endovascular surgical neuro-oncology is a relatively new subspecialty which uses endovascular neuro-interventional techniques for the management of nervous system tumors and tumor-related vascular conditions. Although there are several endovascular procedures that are widely available as standard-of-care diagnostic and treatment adjuncts, there has been a renewed interest to explore endovascular approaches as a means for selective intra-arterial delivery of therapeutic agents to nervous system tumors, including methods for opening the blood brain and blood tumor barriers. In this review, we discuss the historical development of various forms of endovascular intra-arterial treatment for tumors over the past 40 years, summarize endovascular approaches that are currently being employed, and highlight current clinical trials.
AB - Endovascular surgical neuro-oncology is a relatively new subspecialty which uses endovascular neuro-interventional techniques for the management of nervous system tumors and tumor-related vascular conditions. Although there are several endovascular procedures that are widely available as standard-of-care diagnostic and treatment adjuncts, there has been a renewed interest to explore endovascular approaches as a means for selective intra-arterial delivery of therapeutic agents to nervous system tumors, including methods for opening the blood brain and blood tumor barriers. In this review, we discuss the historical development of various forms of endovascular intra-arterial treatment for tumors over the past 40 years, summarize endovascular approaches that are currently being employed, and highlight current clinical trials.
KW - Endovascular neuro-oncology
KW - Immunotherapy
KW - Intra-arterial infusion
KW - Oncolytic virus
KW - Transarterial chemo-embolization
KW - Tumor embolization
KW - Tumor infusion
UR - http://www.scopus.com/inward/record.url?scp=85202974518&partnerID=8YFLogxK
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U2 - 10.1007/s11060-024-04782-4
DO - 10.1007/s11060-024-04782-4
M3 - Review article
C2 - 39222190
AN - SCOPUS:85202974518
SN - 0167-594X
VL - 170
SP - 31
EP - 40
JO - Journal of Neuro-Oncology
JF - Journal of Neuro-Oncology
IS - 1
ER -