Enteropathogenic Escherichia coli: Foe or innocent bystander?

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Enteropathogenic Escherichia coli (EPEC) remain one the most important pathogens infecting children and they are one of the main causes of persistent diarrhoea worldwide. Historically, typical EPEC (tEPEC), defined as those isolates with the attaching and effacement (A/E) genotype (eae<sup>+</sup>), which possess bfpA<sup>+</sup> and lack the stx<sup>-</sup> genes are found strongly associated with diarrhoeal cases. However, occurrence of atypical EPEC (aEPEC; eae<sup>+</sup> bfpA<sup>-</sup> stx<sup>-</sup>) in diarrhoeal and asymptomatic hosts has made investigators question the role of these pathogens in human disease. Current epidemiological data are helping to answer the question of whether EPEC is mainly a foe or an innocent bystander during infection.

Original languageEnglish (US)
Pages (from-to)729-734
Number of pages6
JournalClinical Microbiology and Infection
Volume21
Issue number8
DOIs
StatePublished - Aug 1 2015

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Enteropathogenic Escherichia coli
Diarrhea
Genotype
Research Personnel
Infection
Genes

Keywords

  • Asymptomatic pathogenic escherichia coli
  • Atypical EPEC
  • Diarrhoea
  • Enteropathogenic escherichia coli
  • Epidemiology

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Enteropathogenic Escherichia coli : Foe or innocent bystander? / Hu, J.; Torres, Alfredo.

In: Clinical Microbiology and Infection, Vol. 21, No. 8, 01.08.2015, p. 729-734.

Research output: Contribution to journalArticle

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