Enterovirus 71 infection: Report of an outbreak with two cases of paralysis and a review of the literature

T. Chonmaitree, M. A. Menegus, E. M. Schervish-Swierkosz, E. Schwalenstocker

Research output: Contribution to journalArticlepeer-review

75 Scopus citations

Abstract

Enterovirus 71 (E-71) infection was first reported in 1974 in the United States; subsequent outbreaks were reported in worldwide distribution. In the summer of 1977, we identified 12 patients, mostly children, with E-71 infection. The striking feature of this outbreak is the occurrence of two cases with polio-like paralytic disease. Other diseases associated with E-71 included aseptic meningitis, meningoencephalitis, respiratory disease, gastroenteritis, and hand-foot-mouth disease. The spectrum of illness observed in our community was compared to that seen in other outbreaks. It is suggested that the significance of E-71 lies in its neuropathogenic potential.

Original languageEnglish (US)
Pages (from-to)489-493
Number of pages5
JournalPediatrics
Volume67
Issue number4
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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