Ephrin receptor expression in the embryonic bursa of fabricius

G. T. Pharr, A. M. Cooksey, B. M. McGruder, B. Felfoldi, E. D. Peebles, M. T. Kidd, J. P. Thaxton

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Utilizing degenerate PCR primers complementary to conserved regions within the kinase domain of Receptor Tyrosine Kinase (RTK) genes, the goal was to compare the full complement of RTK expressed (mRNA level) between two developmental stages of bursal B-cells. We identified 21 different RTK cDNAs out of a total of 235 cDNAs sequenced between the two B-cell stages. The dataset revealed the expression of RTK genes important in developmental processes, namely the ephrin receptors (Eph). The ephrin receptors and the ephrin ligands play critical roles in embryo development by controlling the organization of cells in tissues and by inducing cellular differentiation.

Original languageEnglish (US)
Pages (from-to)426-431
Number of pages6
JournalInternational Journal of Poultry Science
Volume8
Issue number5
DOIs
StatePublished - 2009
Externally publishedYes

Fingerprint

receptor protein-tyrosine kinase
Eph Family Receptors
Bursa of Fabricius
bursa of Fabricius
Receptor Protein-Tyrosine Kinases
phosphotransferases (kinases)
tyrosine
B-Lymphocytes
Complementary DNA
receptors
Ephrins
Complement Receptors
B-lymphocytes
Protein-Tyrosine Kinases
Genes
Embryonic Development
Phosphotransferases
Ligands
Polymerase Chain Reaction
Messenger RNA

Keywords

  • B-cell
  • Bursa of fabricius
  • Ephrin receptor
  • Receptor tyrosine kinase

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Food Animals

Cite this

Pharr, G. T., Cooksey, A. M., McGruder, B. M., Felfoldi, B., Peebles, E. D., Kidd, M. T., & Thaxton, J. P. (2009). Ephrin receptor expression in the embryonic bursa of fabricius. International Journal of Poultry Science, 8(5), 426-431. https://doi.org/10.3923/ijps.2009.426.431

Ephrin receptor expression in the embryonic bursa of fabricius. / Pharr, G. T.; Cooksey, A. M.; McGruder, B. M.; Felfoldi, B.; Peebles, E. D.; Kidd, M. T.; Thaxton, J. P.

In: International Journal of Poultry Science, Vol. 8, No. 5, 2009, p. 426-431.

Research output: Contribution to journalArticle

Pharr, GT, Cooksey, AM, McGruder, BM, Felfoldi, B, Peebles, ED, Kidd, MT & Thaxton, JP 2009, 'Ephrin receptor expression in the embryonic bursa of fabricius', International Journal of Poultry Science, vol. 8, no. 5, pp. 426-431. https://doi.org/10.3923/ijps.2009.426.431
Pharr GT, Cooksey AM, McGruder BM, Felfoldi B, Peebles ED, Kidd MT et al. Ephrin receptor expression in the embryonic bursa of fabricius. International Journal of Poultry Science. 2009;8(5):426-431. https://doi.org/10.3923/ijps.2009.426.431
Pharr, G. T. ; Cooksey, A. M. ; McGruder, B. M. ; Felfoldi, B. ; Peebles, E. D. ; Kidd, M. T. ; Thaxton, J. P. / Ephrin receptor expression in the embryonic bursa of fabricius. In: International Journal of Poultry Science. 2009 ; Vol. 8, No. 5. pp. 426-431.
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