Epidemic arboviral diseases: priorities for research and public health

Annelies Wilder-Smith, Duane J. Gubler, Scott C. Weaver, Thomas P. Monath, David L. Heymann, Thomas W. Scott

Research output: Contribution to journalReview article

169 Scopus citations

Abstract

For decades, arboviral diseases were considered to be only minor contributors to global mortality and disability. As a result, low priority was given to arbovirus research investment and related public health infrastructure. The past five decades, however, have seen an unprecedented emergence of epidemic arboviral diseases (notably dengue, chikungunya, yellow fever, and Zika virus disease) resulting from the triad of the modern world: urbanisation, globalisation, and international mobility. The public health emergency of Zika virus, and the threat of global spread of yellow fever, combined with the resurgence of dengue and chikungunya, constitute a wake-up call for governments, academia, funders, and WHO to strengthen programmes and enhance research in aedes-transmitted diseases. The common features of these diseases should stimulate similar research themes for diagnostics, vaccines, biological targets and immune responses, environmental determinants, and vector control measures. Combining interventions known to be effective against multiple arboviral diseases will offer the most cost-effective and sustainable strategy for disease reduction. New global alliances are needed to enable the combination of efforts and resources for more effective and timely solutions.

Original languageEnglish (US)
Pages (from-to)e101-e106
JournalThe Lancet Infectious Diseases
Volume17
Issue number3
DOIs
StatePublished - Mar 1 2017

ASJC Scopus subject areas

  • Infectious Diseases

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    Wilder-Smith, A., Gubler, D. J., Weaver, S. C., Monath, T. P., Heymann, D. L., & Scott, T. W. (2017). Epidemic arboviral diseases: priorities for research and public health. The Lancet Infectious Diseases, 17(3), e101-e106. https://doi.org/10.1016/S1473-3099(16)30518-7