Epidemiological research on hand, foot, and mouth disease in Mainland China

Zhi Chao Zhuang, Zeng Qiang Kou, Yong Juan Bai, Xiang Cong, Li Hong Wang, Chun Li, Li Zhao, Xue Jie Yu, Zhi Yu Wang, Hong Ling Wen

Research output: Contribution to journalReview articlepeer-review

107 Scopus citations


Hand, foot, and mouth disease (HFMD), which has led to millions of attacks and several outbreaks across the world and become more predominant in Asia-Pacific Region, especially in Mainland China, is caused by several Human Enteroviruses including new enterovirus, coxsakievirus and echovirus. In recent years, much research has focused on the epidemiological characteristics of HFMD. In this article, multiple characteristics of HFMD such as basic epidemiology, etiology and molecular epidemiology; influencing factors; detection; and surveillance are reviewed, as these can be help protect high risks groups, prevalence prediction and policy making for disease prevention.

Original languageEnglish (US)
Pages (from-to)6400-6411
Number of pages12
Issue number12
StatePublished - Dec 7 2015


  • Enterovirus
  • Epidemiology
  • Etiology
  • HFMD
  • Influencing factor

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology


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