Epidemiology and laboratory diagnostics of dengue, yellow fever, zika, and chikungunya virus infections in africa

Awadalkareem Adam, Christian Jassoy

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Arbovirus infections are widespread, and their disease burden has increased in the past decade. In Africa, arbovirus infections and fever with unknown etiology are common. Due to the lack of well-established epidemiologic surveillance systems and accurate differential diagnosis in most African countries, little is known about the prevalence of human arbovirus infections in Africa. The aim of this review is to summarize the available epidemiological data and diagnostic laboratory tools of infections with dengue, yellow fever, Zika, and chikungunya viruses, all transmitted by Aedes mosquitoes. Studies indicate that these arboviral infections are endemic in most of Africa. Surveillance of the incidence and prevalence of the infections would enable medical doctors to improve the diagnostic accuracy in patients with typical symptoms. If possible, arboviral diagnostic tests should be added to the routine healthcare systems. Healthcare providers should be informed about the prevalent arboviral diseases to identify possible cases.

Original languageEnglish (US)
Article number1324
Issue number10
StatePublished - Oct 2021
Externally publishedYes


  • Africa
  • Chikungunya virus
  • Dengue virus
  • Epidemiology
  • Laboratory diagnostics
  • Yellow fever virus
  • Zika virus

ASJC Scopus subject areas

  • Immunology and Allergy
  • Molecular Biology
  • General Immunology and Microbiology
  • Microbiology (medical)
  • Infectious Diseases


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