Epidemiology of COVID-19–Associated Mucormycosis

Khadija Tayabali, Hussein Pothiwalla, Shivakumar Narayanan

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Purpose of the Review: To describe the epidemiology and risk factors for Coronavirus disease-19 (COVID-19)–associated mucormycosis (CAM) based on current published literature. Recent Findings: COVID-19 is associated with an increased risk of secondary infections. Mucormycosis is an uncommon invasive fungal infection that typically affects people with immunocompromising conditions and uncontrolled diabetes. Treatment of mucormycosis is challenging and is associated with high mortality even with standard care. During the second wave of the COVID 19 pandemic, an abnormally high number of CAM cases were seen particularly in India. Several case series have attempted to describe the risk factors for CAM. Summary: A common risk profile identified for CAM includes uncontrolled diabetes and treatment with steroids. COVID-19–induced immune dysregulation as well as some unique pandemic specific risk factors may have played a role.

Original languageEnglish (US)
Pages (from-to)156-175
Number of pages20
JournalCurrent Fungal Infection Reports
Volume17
Issue number2
DOIs
StatePublished - Jun 2023
Externally publishedYes

Keywords

  • COVID-19
  • Mucormycosis
  • Rhino-orbito-cerebral
  • Steroid therapy
  • Zygomycosis

ASJC Scopus subject areas

  • Infectious Diseases

Fingerprint

Dive into the research topics of 'Epidemiology of COVID-19–Associated Mucormycosis'. Together they form a unique fingerprint.

Cite this