Epidemiology of methicillin-susceptible staphylococcus aureus in a university medical center day care facility

Angela L. Hewlett, Pamela S. Falk, Katrina S. Hughes, C. Glen Mayhall

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Few data are available on methicillin-susceptible Staphylococcus aureus (MSSA) colonization in day care. We performed a study in a child care center on a medical university campus to study the epidemiology of MSSA in this population. Methods: A cross-sectional study was done on 104 day care attendees and 32 adult employees of the child care center. Swab samples were taken from the nose, oropharynx, axilla, groin, and perirectal area of children, from the nose and oropharynx of employees, and from the environment. Parents and employees completed questionnaires. Swabs were placed in broth, then plated on agar and identified as MSSA by routine methods. Molecular typing was performed. Results: The prevalence of MSSA was 21.15% in children and 28.13% in employees. MSSA was found in 8.72% of environmental samples. Univariate analysis identified 3 risk factors and 5 protective factors for MSSA colonization. In multivariable analysis, only 2 variables remained significantly related to MSSA colonization, with older age remaining as a risk factor and receipt of beta-lactams approaching significance as being protective. Many of the isolates were indistinguishable by molecular typing. Conclusions: The prevalence of MSSA colonization in children and care providers in a university medical center child care center is similar to that of the general population. Children colonized with MSSA tended to be older and to have received fewer courses of antibiotics than children who did not have MSSA. The relatedness of many of the isolates indicates that transmission of MSSA occurred at this child care center.

Original languageEnglish (US)
Pages (from-to)145-147
Number of pages3
JournalPediatric Infectious Disease Journal
Volume29
Issue number2
DOIs
StatePublished - Feb 2010

Fingerprint

Methicillin
Medical Day Care
Staphylococcus aureus
Epidemiology
Child Care
Molecular Typing
Oropharynx
Nose
Axilla
Groin
beta-Lactams
Population
Agar
Cross-Sectional Studies
Parents
Anti-Bacterial Agents

Keywords

  • Child care
  • Day care
  • MSSA
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)

Cite this

Epidemiology of methicillin-susceptible staphylococcus aureus in a university medical center day care facility. / Hewlett, Angela L.; Falk, Pamela S.; Hughes, Katrina S.; Mayhall, C. Glen.

In: Pediatric Infectious Disease Journal, Vol. 29, No. 2, 02.2010, p. 145-147.

Research output: Contribution to journalArticle

Hewlett, Angela L. ; Falk, Pamela S. ; Hughes, Katrina S. ; Mayhall, C. Glen. / Epidemiology of methicillin-susceptible staphylococcus aureus in a university medical center day care facility. In: Pediatric Infectious Disease Journal. 2010 ; Vol. 29, No. 2. pp. 145-147.
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