Epidemiology, pathogenesis, and treatment of gallstones

Willemijntje A. Hoogerwerf, Roger D. Soloway

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


During the past year several epidemiologic reports have confirmed a number of long-held clinical impressions concerning the importance of various risk factors for gallstone disease. Disappointingly there were no new insights in this area. In the area of pathogenesis, studies have suggested additional pronucleating factors. The most important of these have examined nonprotein factors in bile. Laparoscopic cholecystectomy remains the treatment of choice for cholelithiasis. The course of stone recurrence after medical treatment continues to be defined and supports the opinion that solitary stones and multiple cholesterol gallstones should be viewed as manifestations of different diseases.

Original languageEnglish (US)
Pages (from-to)413-416
Number of pages4
JournalCurrent Opinion in Gastroenterology
Issue number5
StatePublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Gastroenterology


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