Escherichia coli lobar pneumonia: Fatal infection in a patient with mental retardation

Pamela B. Jaffey, Paul W. English, Gerald A. Campbell, Sanford A. Rubin, Abida K. Haque

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Lobar pneumonia due to Escherichia coli is rare. Most lobar pneumonias are caused by either Streptococcus pneumoniae or Klebsiella pneumoniae, and most E coli pneumonias are bronchopneumonias. We report an acute fulminant course of E coli lobar pneumonia in a 37-year-old patient who was profoundly retarded, institutionalized, and nonimmunosuppressed and who died within 2 days of developing initial symptoms. Antemortem blood and postmortem blood and lung specimens isolated pure cultures of E coli. The source of infection in E coli lobar pneumonia is not clear in this patient or in the few cases that have been reported. We postulate that nasopharyngeal colonization of E coli in those who are institutionalized with mental retardation may predispose these patients to E coli pneumonia. Our case illustrates features of pneumonias that are unique in the institutionalized, mentally retarded patient population (ie, the relatively high prevalence of nasopharyngeal colonization of E coli, a higher incidence of E coli pneumonia than in other institutionalized populations, the often fulminant course of the disease), as well as the need for early, aggressive treatment including antibiotics effective against gram-negative bacteria.

Original languageEnglish (US)
Pages (from-to)628-630
Number of pages3
JournalSouthern medical journal
Volume89
Issue number6
DOIs
StatePublished - Jan 1 1996

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Escherichia coli lobar pneumonia: Fatal infection in a patient with mental retardation'. Together they form a unique fingerprint.

Cite this