Escherichia coli lobar pneumonia

Fatal infection in a patient with mental retardation

Pamela B. Jaffey, Paul W. English, Gerald Campbell, Sanford A. Rubin, Abida K. Haque

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Lobar pneumonia due to Escherichia coli is rare. Most lobar pneumonias are caused by either Streptococcus pneumoniae or Klebsiella pneumoniae, and most E coli pneumonias are bronchopneumonias. We report an acute fulminant course of E coli lobar pneumonia in a 37-year-old patient who was profoundly retarded, institutionalized, and nonimmunosuppressed and who died within 2 days of developing initial symptoms. Antemortem blood and postmortem blood and lung specimens isolated pure cultures of E coli. The source of infection in E coli lobar pneumonia is not clear in this patient or in the few cases that have been reported. We postulate that nasopharyngeal colonization of E coli in those who are institutionalized with mental retardation may predispose these patients to E coli pneumonia. Our case illustrates features of pneumonias that are unique in the institutionalized, mentally retarded patient population (ie, the relatively high prevalence of nasopharyngeal colonization of E coli, a higher incidence of E coli pneumonia than in other institutionalized populations, the often fulminant course of the disease), as well as the need for early, aggressive treatment including antibiotics effective against gram-negative bacteria.

Original languageEnglish (US)
Pages (from-to)628-630
Number of pages3
JournalSouthern Medical Journal
Volume89
Issue number6
StatePublished - 1996

Fingerprint

Intellectual Disability
Pneumonia
Escherichia coli
Infection
Bronchopneumonia
Escherichia coli Infections
Mentally Disabled Persons
Klebsiella pneumoniae
Streptococcus pneumoniae
Gram-Negative Bacteria
Population
Anti-Bacterial Agents
Lung
Incidence

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Jaffey, P. B., English, P. W., Campbell, G., Rubin, S. A., & Haque, A. K. (1996). Escherichia coli lobar pneumonia: Fatal infection in a patient with mental retardation. Southern Medical Journal, 89(6), 628-630.

Escherichia coli lobar pneumonia : Fatal infection in a patient with mental retardation. / Jaffey, Pamela B.; English, Paul W.; Campbell, Gerald; Rubin, Sanford A.; Haque, Abida K.

In: Southern Medical Journal, Vol. 89, No. 6, 1996, p. 628-630.

Research output: Contribution to journalArticle

Jaffey, PB, English, PW, Campbell, G, Rubin, SA & Haque, AK 1996, 'Escherichia coli lobar pneumonia: Fatal infection in a patient with mental retardation', Southern Medical Journal, vol. 89, no. 6, pp. 628-630.
Jaffey, Pamela B. ; English, Paul W. ; Campbell, Gerald ; Rubin, Sanford A. ; Haque, Abida K. / Escherichia coli lobar pneumonia : Fatal infection in a patient with mental retardation. In: Southern Medical Journal. 1996 ; Vol. 89, No. 6. pp. 628-630.
@article{3521015af32f423989e57334eb1759fa,
title = "Escherichia coli lobar pneumonia: Fatal infection in a patient with mental retardation",
abstract = "Lobar pneumonia due to Escherichia coli is rare. Most lobar pneumonias are caused by either Streptococcus pneumoniae or Klebsiella pneumoniae, and most E coli pneumonias are bronchopneumonias. We report an acute fulminant course of E coli lobar pneumonia in a 37-year-old patient who was profoundly retarded, institutionalized, and nonimmunosuppressed and who died within 2 days of developing initial symptoms. Antemortem blood and postmortem blood and lung specimens isolated pure cultures of E coli. The source of infection in E coli lobar pneumonia is not clear in this patient or in the few cases that have been reported. We postulate that nasopharyngeal colonization of E coli in those who are institutionalized with mental retardation may predispose these patients to E coli pneumonia. Our case illustrates features of pneumonias that are unique in the institutionalized, mentally retarded patient population (ie, the relatively high prevalence of nasopharyngeal colonization of E coli, a higher incidence of E coli pneumonia than in other institutionalized populations, the often fulminant course of the disease), as well as the need for early, aggressive treatment including antibiotics effective against gram-negative bacteria.",
author = "Jaffey, {Pamela B.} and English, {Paul W.} and Gerald Campbell and Rubin, {Sanford A.} and Haque, {Abida K.}",
year = "1996",
language = "English (US)",
volume = "89",
pages = "628--630",
journal = "Southern Medical Journal",
issn = "0038-4348",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Escherichia coli lobar pneumonia

T2 - Fatal infection in a patient with mental retardation

AU - Jaffey, Pamela B.

AU - English, Paul W.

AU - Campbell, Gerald

AU - Rubin, Sanford A.

AU - Haque, Abida K.

PY - 1996

Y1 - 1996

N2 - Lobar pneumonia due to Escherichia coli is rare. Most lobar pneumonias are caused by either Streptococcus pneumoniae or Klebsiella pneumoniae, and most E coli pneumonias are bronchopneumonias. We report an acute fulminant course of E coli lobar pneumonia in a 37-year-old patient who was profoundly retarded, institutionalized, and nonimmunosuppressed and who died within 2 days of developing initial symptoms. Antemortem blood and postmortem blood and lung specimens isolated pure cultures of E coli. The source of infection in E coli lobar pneumonia is not clear in this patient or in the few cases that have been reported. We postulate that nasopharyngeal colonization of E coli in those who are institutionalized with mental retardation may predispose these patients to E coli pneumonia. Our case illustrates features of pneumonias that are unique in the institutionalized, mentally retarded patient population (ie, the relatively high prevalence of nasopharyngeal colonization of E coli, a higher incidence of E coli pneumonia than in other institutionalized populations, the often fulminant course of the disease), as well as the need for early, aggressive treatment including antibiotics effective against gram-negative bacteria.

AB - Lobar pneumonia due to Escherichia coli is rare. Most lobar pneumonias are caused by either Streptococcus pneumoniae or Klebsiella pneumoniae, and most E coli pneumonias are bronchopneumonias. We report an acute fulminant course of E coli lobar pneumonia in a 37-year-old patient who was profoundly retarded, institutionalized, and nonimmunosuppressed and who died within 2 days of developing initial symptoms. Antemortem blood and postmortem blood and lung specimens isolated pure cultures of E coli. The source of infection in E coli lobar pneumonia is not clear in this patient or in the few cases that have been reported. We postulate that nasopharyngeal colonization of E coli in those who are institutionalized with mental retardation may predispose these patients to E coli pneumonia. Our case illustrates features of pneumonias that are unique in the institutionalized, mentally retarded patient population (ie, the relatively high prevalence of nasopharyngeal colonization of E coli, a higher incidence of E coli pneumonia than in other institutionalized populations, the often fulminant course of the disease), as well as the need for early, aggressive treatment including antibiotics effective against gram-negative bacteria.

UR - http://www.scopus.com/inward/record.url?scp=0029905479&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029905479&partnerID=8YFLogxK

M3 - Article

VL - 89

SP - 628

EP - 630

JO - Southern Medical Journal

JF - Southern Medical Journal

SN - 0038-4348

IS - 6

ER -