Ethanol-withdrawal syndrome associated with both general and localized increases in glucose uptake in rat brain

Gerald A. Campbell, Michael J. Eckardt, Edward Majchrowicz, Cheryl A. Marietta, Forrest F. Weight

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Glucose uptake was studied in the brains of rats undergoing an overt ethanol-withdrawal syndrome by 2-deoxy-d-[14C]glucose autoradiography. In addition to a general increase in glucose uptake, localized alterations were observed in sensorimotor cortex, globus pallidus, thalamus and cerebellum. The results suggest that the ethanol-withdrawal syndrome is associated with a general increase in glucose metabolism as well as localized increases in functionally distinct regions of sensory and motor brain regions.

Original languageEnglish (US)
Pages (from-to)517-522
Number of pages6
JournalBrain Research
Volume237
Issue number2
DOIs
StatePublished - Apr 15 1982
Externally publishedYes

Keywords

  • 2-deoxyglucose
  • ethanol-withdrawal syndrome

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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