Ethanol-withdrawal syndrome associated with both general and localized increases in glucose uptake in rat brain

Gerald Campbell, Michael J. Eckardt, Edward Majchrowicz, Cheryl A. Marietta, Forrest F. Weight

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Glucose uptake was studied in the brains of rats undergoing an overt ethanol-withdrawal syndrome by 2-deoxy-d-[14C]glucose autoradiography. In addition to a general increase in glucose uptake, localized alterations were observed in sensorimotor cortex, globus pallidus, thalamus and cerebellum. The results suggest that the ethanol-withdrawal syndrome is associated with a general increase in glucose metabolism as well as localized increases in functionally distinct regions of sensory and motor brain regions.

Original languageEnglish (US)
Pages (from-to)517-522
Number of pages6
JournalBrain Research
Volume237
Issue number2
DOIs
StatePublished - Apr 15 1982
Externally publishedYes

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Keywords

  • 2-deoxyglucose
  • ethanol-withdrawal syndrome

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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