Ethnic differences in heterotopic ossification following total hip arthroplasty

G. Davis, R. P. Patel, T. L. Tan, P. Alijanipour, T. U. Naik, J. Parvizi

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Aims: We aimed to assess the influence of ethnicity on the incidence of heterotopic ossification (HO) after total hip arthroplasty (THA). Patients and Methods: We studied the six-month post-operative anteroposterior radiographs of 1449 consecutive primary THAs (1324 patients) and retrospectively graded them for the presence of HO, using the Brooker Classification. Results: Based on multivariate analysis, African-American ethnicity was an independent risk factor for HO formation following THA with an adjusted odds ratio (OR) of 2.6 (95% confidence interval (CI) 1.3 to 5.2, p = 0.007) for severe HO and 1.9 (95% CI 1.3 to 2.7, p < 0.001) for any grade of HO. Conclusion: Given the increased risk of HO formation, particularly high grade HO, and the potentially poorer outcomes associated with HO, it is important to consider using prophylaxis against HO in patients of African-American ethnicity undergoing THA.

Original languageEnglish (US)
Pages (from-to)761-766
Number of pages6
JournalBone and Joint Journal
Issue number6
StatePublished - Jun 2016
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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