Ethnicity, type 2 diabetes & migrant Asian Indians

Nicola Abate, Manisha Chandalia

Research output: Contribution to journalReview article

55 Scopus citations

Abstract

The rapid increase of diabetes prevalence in the US population and across all westernized world has been associated with environmental changes that promote obesity. However, studies conducted in various ethnic groups within the US population have pointed out differences in susceptibility to diabetes within the same environmental pressure. Of particular interest is the growing evidence that Asian Indians, i.e., persons originating from the Indian Subcontinent, are at uniquely heightened risk for type 2 diabetes when compared to other populations. The elucidation of the mechanisms responsible for the heterogeneous relationship between obesity and type 2 diabetes in various ethnic groups, and particularly in Asian Indians, may give important contributions to better understand the complex mechanisms involved in the development of type 2 diabetes. This review examines epidemiological and pathophysiological aspects of the interaction between environment and ethnic predisposition to type 2 diabetes in Asian Indians migrated to the US.

Original languageEnglish (US)
Pages (from-to)251-258
Number of pages8
JournalIndian Journal of Medical Research
Volume125
Issue number3
StatePublished - Mar 1 2007

Keywords

  • Asian Indian
  • Beta-cell dysfunction
  • Ethnicity
  • Insulin resistance
  • Type 2 diabetes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Abate, N., & Chandalia, M. (2007). Ethnicity, type 2 diabetes & migrant Asian Indians. Indian Journal of Medical Research, 125(3), 251-258.