EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator

Keyphrases

• Repressor 100%
• Mycobacterium 100%
• TetR 100%
• Ethionamide Resistance 100%
• EthA 100%
• EthR 100%
• Ethionamide 66%
• Binding Region 22%
• Promoter Region 22%
• Electrophoretic Mobility Shift Assay 11%
• Gel Filtration 11%
• Prodrug 11%
• Drug Use 11%
• Mycobacterium Tuberculosis (M. tb) 11%
• Dimerization 11%
• Cross-resistance 11%
• Culture Media 11%
• Negatively Regulate 11%
• Antimicrobial Activity 11%
• Transcriptional Regulator 11%
• Transcription Start Site 11%
• Structural Analogues 11%
• Strong Inhibition 11%
• Primer Extension 11%
• Gene Overexpression 11%
• Multimerization 11%
• Filtration Assay 11%
• Surface Plasmon Resonance Analysis 11%
• DNA Footprinting 11%
• LacZ Reporter Gene 11%
• Flavin-dependent Monooxygenase 11%
• Multidrug-resistant Mycobacterium Tuberculosis 11%
• Antitubercular Agents 11%
• Bacterial Two-hybrid System 11%
• Hybrid Gel 11%
• Hybrid Experiments 11%

Biochemistry, Genetics and Molecular Biology

• Repressor 100%
• Mycobacteria 100%
• Promoter Region 66%
• Enzyme 33%
• Reporter Gene 33%
• Gel Filtration 33%
• Dimerization 33%
• Cross Resistance 33%
• Electrophoretic Mobility Shift Assay 33%
• Primer Extension 33%
• Multimerization 33%
• Surface Plasmon Resonance 33%
• Mycobacterium Tuberculosis 33%
• Antimicrobial Activity 33%
• Gene Overexpression 33%
• Flavin-Containing Monooxygenase 33%
• DNA Footprinting 33%

Immunology and Microbiology

• Repressor Gene 100%
• Mycobacteria 100%
• Promoter Region 66%
• Gel Mobility Shift Assay 33%
• Gel Filtration 33%
• Reporter Gene 33%
• Mycobacterium Tuberculosis 33%
• Dimerization 33%
• Cross-Resistance 33%
• Antimicrobial Activity 33%
• Surface Plasmon Resonance 33%
• DNA Footprinting 33%
• Gene Overexpression 33%
• Antimicrobial Agent 33%