Etiología y caracterización epidemiológica del síndrome febril no palúdico en tres municipios del Urabá antioqueño, Colombia

Translated title of the contribution: Etiology and epidemiological characterization of non-malarial febrile syndrome in three municipalities of urabá (antioquia), Colombia

Esteban Arroyave, Andrés Felipe Londoño, Juan Carlos Quintero, Piedad Agudelo-Flórez, Margarita Arboleda, Francisco J. Díaz, Juan D. Rodas

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Introduction: Urabá, a region on the northern coast of Colombia, is endemic to several acute febrile illnesses of infectious origin; however, only patients with malaria may have access to quick and effective diagnosis. For this reason, many non-malarial febrile patients go without a clear etiologic diagnosis. Aim: To establish the etiology and clinical signs of acute febrile non-malaria syndromes and explore some of the likely risk factors in patients originating in the municipalities of Necocli, Turbo and Apartado who exhibit these symptoms. Materials and methods: We obtained acute and convalescent sera from 220 non-malarial febrile patients from the rural and urban zones of Necocli, Turbo and Apartado during 2007 and 2008. Serologic tests for dengue (IgM by ELISA), leptospirosis (IgM and IgG by IFA), rickettsiosis (IgG by IFI), hanta and arenavirus (IgG by ELISA) were performed. Results: We found that the frequency of infection for dengue, leptospirosis, rickettsiosis and arenavirus, was 37.3%; 14.1%; 2.7% and 0.5%, respectively. There were 12 co-infection cases of leptospirosis-dengue and one of leptospirosis-rickettsiosis-dengue. Male gender and relative humidity were considered risk factors for dengue, and the beginning of clinical signs in February of 2008 was associated with the infection of dengue and leptospirosis. Conclusion: This study confirms previous records that underline the importance of Rickettsia spp, dengue virus and Leptospira spp as causal agents of febrile syndrome in this region of Colombia.

Translated title of the contributionEtiology and epidemiological characterization of non-malarial febrile syndrome in three municipalities of urabá (antioquia), Colombia
Original languageSpanish
Pages (from-to)99-107
Number of pages9
JournalBiomedica
Volume33
Issue numberSUPPL.1
DOIs
StatePublished - Sep 1 2013
Externally publishedYes

Keywords

  • Colombia
  • Epidemiological surveillance
  • Febrile syndrome
  • Serological tests
  • Zoonoses

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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