Evaluation and management of acute pancreatitis

Ahmed T. Chatila, Mohammad Bilal, Praveen Guturu

Research output: Contribution to journalReview articlepeer-review

65 Scopus citations


Acute pancreatitis (AP) is one of the most common gastrointestinal causes for hospi-talization in the United States. In 2015, AP accounted for approximately 390000 hospitalizations. The burden of AP is only expected to increase over time. Despite recent advances in medicine, pancreatitis continues to be associated with a substantial morbidity and mortality. The most common cause of AP is gallstones, followed closely by alcohol use. The diagnosis of pancreatitis is established with any two of three following criteria: (1) Abdominal pain consistent with that of AP; (2) Serum amylase and/or lipase greater than three times the upper limit of normal; and (3) Characteristics findings seen in crosssectional abdominal imaging. Multiple criteria and scoring systems have been established for assessing severity of AP. The cornerstones of management include aggressive intravenous hydration, appropriate nutrition and pain management. Endoscopic retrograde cholangiopancreatography and surgery are important aspects in management of acute gallstone pancreatitis. We provide a comprehensive review of evaluation and management of AP.

Original languageEnglish (US)
Pages (from-to)1006-1020
Number of pages15
JournalWorld Journal of Clinical Cases
Issue number9
StatePublished - 2019


  • Acute pancreatitis
  • Gallstone pancreatitis
  • Necrotizing pancreatitis
  • Resuscitation

ASJC Scopus subject areas

  • General Medicine


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