Evaluation of a multiplex bead immunoassay for determination of immune status to varicella-zoster virus in medical center students and employees

Michael J. Loeffelholz, Harry E. Prince

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This study evaluated an enzyme immunoassay, a multiplex bead immunoassay (MBIA), and the anticomplement immunofluorescence (ACIF) test for detecting varicella-zoster virus IgG antibodies in sera from medical center students and employees. The agreement between methods was ≥95%. The MBIA was less sensitive than was the ACIF test, with a negative predictive value of 66.7%.

Original languageEnglish (US)
Pages (from-to)351-353
Number of pages3
JournalClinical and Vaccine Immunology
Volume22
Issue number3
DOIs
StatePublished - Mar 1 2015

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Human Herpesvirus 3
Medical Students
Viruses
Immunoassay
Fluorescent Antibody Technique
Personnel
Students
Immunoenzyme Techniques
Immunoglobulin G
Antibodies
Enzymes
Serum
anticomplement

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Immunology
  • Immunology and Allergy
  • Microbiology (medical)

Cite this

Evaluation of a multiplex bead immunoassay for determination of immune status to varicella-zoster virus in medical center students and employees. / Loeffelholz, Michael J.; Prince, Harry E.

In: Clinical and Vaccine Immunology, Vol. 22, No. 3, 01.03.2015, p. 351-353.

Research output: Contribution to journalArticle

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