Evaluation of pain and stress in healthy volunteers undergoing research lumbar punctures

Gabrielle Page-Wilson; Sharon L. Wardlaw; Kim T. Nguyen; Richard M. Smiley

doi:10.1212/WNL.0000000000002894

Evaluation of pain and stress in healthy volunteers undergoing research lumbar punctures

Gabrielle Page-Wilson, Sharon L. Wardlaw, Kim T. Nguyen, Richard M. Smiley

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

The use of lumbar punctures (LPs) in clinical research is increasing as emerging data demonstrate that CSF biomarkers can provide useful information about neurophysiology and the pathogenesis of diseases such as Alzheimer disease, amyotrophic lateral sclerosis, and Parkinson disease. Given the invasive nature of LPs, we sought to prospectively evaluate pain and hormonal indices of stress in participants undergoing research LPs in order to improve the quality of informed consent.

Original language	English (US)
Pages (from-to)	438-439
Number of pages	2
Journal	Neurology
Volume	87
Issue number	4
DOIs	https://doi.org/10.1212/WNL.0000000000002894
State	Published - Jul 26 2016
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

Access to Document

10.1212/WNL.0000000000002894

Cite this

@article{6708f755d69b44c5a8f26b8bdc7fd044,

title = "Evaluation of pain and stress in healthy volunteers undergoing research lumbar punctures",

abstract = "The use of lumbar punctures (LPs) in clinical research is increasing as emerging data demonstrate that CSF biomarkers can provide useful information about neurophysiology and the pathogenesis of diseases such as Alzheimer disease, amyotrophic lateral sclerosis, and Parkinson disease. Given the invasive nature of LPs, we sought to prospectively evaluate pain and hormonal indices of stress in participants undergoing research LPs in order to improve the quality of informed consent.",

author = "Gabrielle Page-Wilson and Wardlaw, \{Sharon L.\} and Nguyen, \{Kim T.\} and Smiley, \{Richard M.\}",

note = "Publisher Copyright: {\textcopyright} 2016 American Academy of Neurology.",

year = "2016",

month = jul,

day = "26",

doi = "10.1212/WNL.0000000000002894",

language = "English (US)",

volume = "87",

pages = "438--439",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

number = "4",

}

TY - JOUR

T1 - Evaluation of pain and stress in healthy volunteers undergoing research lumbar punctures

AU - Page-Wilson, Gabrielle

AU - Wardlaw, Sharon L.

AU - Nguyen, Kim T.

AU - Smiley, Richard M.

PY - 2016/7/26

Y1 - 2016/7/26

N2 - The use of lumbar punctures (LPs) in clinical research is increasing as emerging data demonstrate that CSF biomarkers can provide useful information about neurophysiology and the pathogenesis of diseases such as Alzheimer disease, amyotrophic lateral sclerosis, and Parkinson disease. Given the invasive nature of LPs, we sought to prospectively evaluate pain and hormonal indices of stress in participants undergoing research LPs in order to improve the quality of informed consent.

AB - The use of lumbar punctures (LPs) in clinical research is increasing as emerging data demonstrate that CSF biomarkers can provide useful information about neurophysiology and the pathogenesis of diseases such as Alzheimer disease, amyotrophic lateral sclerosis, and Parkinson disease. Given the invasive nature of LPs, we sought to prospectively evaluate pain and hormonal indices of stress in participants undergoing research LPs in order to improve the quality of informed consent.

UR - https://www.scopus.com/pages/publications/84980329235

UR - https://www.scopus.com/inward/citedby.url?scp=84980329235&partnerID=8YFLogxK

U2 - 10.1212/WNL.0000000000002894

DO - 10.1212/WNL.0000000000002894

M3 - Short survey

C2 - 27358342

AN - SCOPUS:84980329235

SN - 0028-3878

VL - 87

SP - 438

EP - 439

JO - Neurology

JF - Neurology

IS - 4

ER -

Evaluation of pain and stress in healthy volunteers undergoing research lumbar punctures

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this