Evidence against person-to-person transmission of hantavirus to health care workers

Charles R. Vitek, Robert F. Breiman, Thomas Ksiazek, Pierre E. Rollin, James C. McLaughlin, Edith T. Umland, Kurt B. Nolte, Arnold Loera, C. Mack Sewell, C. J. Peters

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Unusual, primarily pulmonary, manifestations of hantaviral illness occurring in the southwestern United States raised the possibility of person- to-person transmission of a recently recognized hantavirus, Sin Nombre virus. To determine whether such transmission had occurred among health care workers (HCWs) exposed to patients with confirmed hantavirus pulmonary syndrome, we evaluated HCWs who had cared for patients with hantavirus pulmonary syndrome or who had processed specimens from these patients. Information about exposure to these patients and about recent illnesses was obtained via a standardized questionnaire. Serum specimens were tested for IgM and IgG antibodies to hantaviruses with use of ELISAs. Of the 396 HCWs, 266 (67%) reported that they had been exposed to patients with hantavirus pulmonary syndrome or to their body fluids or that they had processed laboratory specimens from these patients. Although 108 (27%) of the HCWs reported fever, myalgias, or respiratory illnesses during the 3 months before the serum specimens were obtained, hantavirus antibodies were not detected in any HCW. These data suggest that person-to-person transmission of Sin Nombre virus is unlikely to occur in health care settings.

Original languageEnglish (US)
Pages (from-to)824-826
Number of pages3
JournalClinical Infectious Diseases
Volume22
Issue number5
StatePublished - May 1996
Externally publishedYes

Fingerprint

Hantavirus
Hantavirus Pulmonary Syndrome
Delivery of Health Care
Sin Nombre virus
Southwestern United States
Antibodies
Myalgia
Body Fluids
Serum
Immunoglobulin M
Fever
Immunoglobulin G
Enzyme-Linked Immunosorbent Assay
Lung

ASJC Scopus subject areas

  • Immunology

Cite this

Vitek, C. R., Breiman, R. F., Ksiazek, T., Rollin, P. E., McLaughlin, J. C., Umland, E. T., ... Peters, C. J. (1996). Evidence against person-to-person transmission of hantavirus to health care workers. Clinical Infectious Diseases, 22(5), 824-826.

Evidence against person-to-person transmission of hantavirus to health care workers. / Vitek, Charles R.; Breiman, Robert F.; Ksiazek, Thomas; Rollin, Pierre E.; McLaughlin, James C.; Umland, Edith T.; Nolte, Kurt B.; Loera, Arnold; Sewell, C. Mack; Peters, C. J.

In: Clinical Infectious Diseases, Vol. 22, No. 5, 05.1996, p. 824-826.

Research output: Contribution to journalArticle

Vitek, CR, Breiman, RF, Ksiazek, T, Rollin, PE, McLaughlin, JC, Umland, ET, Nolte, KB, Loera, A, Sewell, CM & Peters, CJ 1996, 'Evidence against person-to-person transmission of hantavirus to health care workers', Clinical Infectious Diseases, vol. 22, no. 5, pp. 824-826.
Vitek CR, Breiman RF, Ksiazek T, Rollin PE, McLaughlin JC, Umland ET et al. Evidence against person-to-person transmission of hantavirus to health care workers. Clinical Infectious Diseases. 1996 May;22(5):824-826.
Vitek, Charles R. ; Breiman, Robert F. ; Ksiazek, Thomas ; Rollin, Pierre E. ; McLaughlin, James C. ; Umland, Edith T. ; Nolte, Kurt B. ; Loera, Arnold ; Sewell, C. Mack ; Peters, C. J. / Evidence against person-to-person transmission of hantavirus to health care workers. In: Clinical Infectious Diseases. 1996 ; Vol. 22, No. 5. pp. 824-826.
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