Evidence for different transport systems for oxidized glutathione and S-dinitrophenyl glutathione in human erythrocytes

E. F. LaBelle, S. V. Singh, S. K. Srivastava, Y. C. Awasthi

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

The effect of oxidized glutathione (GSSG) on the ATP-dependent transport of S-dinitrophenyl glutathione (Dnp-SG) by inside-out vesicles prepared from human erythrocytes and by intact erythrocytes has been studied. It is demonstrated that the transport of Dnp-SG is not inhibited by GSSG in either intact erythrocytes or in inside-out vesicles. These results suggest that Dnp-SG and GSSG are transported out of human erythrocytes by separate systems.

Original languageEnglish (US)
Pages (from-to)538-544
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume139
Issue number2
DOIs
StatePublished - Sep 16 1986

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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