Evidence for different transport systems for oxidized glutathione and S-dinitrophenyl glutathione in human erythrocytes

E. F. LaBelle, S. V. Singh, Satish Srivastava, Y. C. Awasthi

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The effect of oxidized glutathione (GSSG) on the ATP-dependent transport of S-dinitrophenyl glutathione (Dnp-SG) by inside-out vesicles prepared from human erythrocytes and by intact erythrocytes has been studied. It is demonstrated that the transport of Dnp-SG is not inhibited by GSSG in either intact erythrocytes or in inside-out vesicles. These results suggest that Dnp-SG and GSSG are transported out of human erythrocytes by separate systems.

Original languageEnglish (US)
Pages (from-to)538-544
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume139
Issue number2
DOIs
StatePublished - Sep 16 1986

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Glutathione Disulfide
Glutathione
Erythrocytes
Adenosine Triphosphate

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Evidence for different transport systems for oxidized glutathione and S-dinitrophenyl glutathione in human erythrocytes. / LaBelle, E. F.; Singh, S. V.; Srivastava, Satish; Awasthi, Y. C.

In: Biochemical and Biophysical Research Communications, Vol. 139, No. 2, 16.09.1986, p. 538-544.

Research output: Contribution to journalArticle

LaBelle, E. F. ; Singh, S. V. ; Srivastava, Satish ; Awasthi, Y. C. / Evidence for different transport systems for oxidized glutathione and S-dinitrophenyl glutathione in human erythrocytes. In: Biochemical and Biophysical Research Communications. 1986 ; Vol. 139, No. 2. pp. 538-544.
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