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Evolution of a cell culture-derived genotype 1a hepatitis C Virus (H77S.2) during persistent infection with chronic hepatitis in a Chimpanzee
Min Kyung Yi
, Fengyu Hu
, Michael Joyce
, Vikas Saxena
, Christoph Welsch
, Deborah Chavez
, Bernadette Guerra
, Daisuke Yamane
, Ronald Veselenak
,
Rick Pyles
, Christopher M. Walker
, Lorne Tyrrell
,
Nigel Bourne
, Robert E. Lanford
, Stanley M. Lemon
Microbiology And Immunology
Pediatrics
Research output
:
Contribution to journal
›
Article
›
peer-review
25
Scopus citations
Overview
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Keyphrases
Virus
100%
Hepatitis C Virus
100%
Chronic Hepatitis
100%
Persistent Infection
100%
Genotype 1
100%
Chimpanzee
100%
Cell Culture-derived
100%
Cell Culture
85%
JFH1
42%
Adaptive mutation
42%
Transient Infection
28%
Pathogenicity
28%
Type Sequences
28%
Liver
14%
Innate Immune Response
14%
NS5A
14%
Hepatopathy
14%
Seroconversion
14%
Alanine Aminotransferase Elevation
14%
Selective Pressure
14%
Chimeric Virus
14%
Persistent Viremia
14%
Synonymous nucleotide Substitution
14%
NsSNPs
14%
Nucleotide Substitution Rate
14%
Detectable Viremia
14%
Immunology and Microbiology
Cell Culture
100%
Hepatitis C Virus Subtype 1a
100%
Infection
100%
Virus
88%
Wild Type
22%
Pathogenicity
22%
Hepatitis C Virus
22%
Viremia
22%
Innate Immune System
11%
NS5A
11%
Seroconversion
11%
Alanine
11%