Evolution of new genotype of west nile virus in North America

Allison R. McMullen, Fiona J. May, Li Li, Hilda Guzman, Rudy Bueno, James A. Dennett, Robert B. Tesh, Alan Barrett

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Previous studies of North American isolates of West Nile virus (WNV) during 1999-2005 suggested that the virus had reached genetic homeostasis in North America. However, genomic sequencing of WNV isolates from Harris County, Texas, during 2002-2009 suggests that this is not the case. Three new genetic groups have been identifi ed in Texas since 2005. Spread of the southwestern US genotype (SW/WN03) from the Arizona/Colorado/northern Mexico region to California, Illinois, New Mexico, New York, North Dakota, and the Texas Gulf Coast demonstrates continued evolution of WNV. Thus, WNV continues to evolve in North America, as demonstrated by selection of this new genotype. Continued surveillance of the virus is essential as it continues to evolve in the New World.

Original languageEnglish (US)
Pages (from-to)785-793
Number of pages9
JournalEmerging Infectious Diseases
Volume17
Issue number5
DOIs
StatePublished - 2011

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West Nile virus
North America
Genotype
Viruses
Mexico
Homeostasis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Epidemiology

Cite this

McMullen, A. R., May, F. J., Li, L., Guzman, H., Bueno, R., Dennett, J. A., ... Barrett, A. (2011). Evolution of new genotype of west nile virus in North America. Emerging Infectious Diseases, 17(5), 785-793. https://doi.org/10.3201/eid1705.101707

Evolution of new genotype of west nile virus in North America. / McMullen, Allison R.; May, Fiona J.; Li, Li; Guzman, Hilda; Bueno, Rudy; Dennett, James A.; Tesh, Robert B.; Barrett, Alan.

In: Emerging Infectious Diseases, Vol. 17, No. 5, 2011, p. 785-793.

Research output: Contribution to journalArticle

McMullen, AR, May, FJ, Li, L, Guzman, H, Bueno, R, Dennett, JA, Tesh, RB & Barrett, A 2011, 'Evolution of new genotype of west nile virus in North America', Emerging Infectious Diseases, vol. 17, no. 5, pp. 785-793. https://doi.org/10.3201/eid1705.101707
McMullen AR, May FJ, Li L, Guzman H, Bueno R, Dennett JA et al. Evolution of new genotype of west nile virus in North America. Emerging Infectious Diseases. 2011;17(5):785-793. https://doi.org/10.3201/eid1705.101707
McMullen, Allison R. ; May, Fiona J. ; Li, Li ; Guzman, Hilda ; Bueno, Rudy ; Dennett, James A. ; Tesh, Robert B. ; Barrett, Alan. / Evolution of new genotype of west nile virus in North America. In: Emerging Infectious Diseases. 2011 ; Vol. 17, No. 5. pp. 785-793.
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