Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle

Jared M. Dickinson, Elena Volpi, Blake B. Rasmussen

    Research output: Contribution to journalArticlepeer-review

    66 Scopus citations

    Abstract

    The loss of skeletal muscle size and function with aging and sarcopenia may be related, in part, to an age-related muscle protein synthesis impairment. In this review, we discuss to what extent aging affects skeletal muscle protein synthesis and how nutrition and exercise can be used strategically to overcome age-related protein synthesis impairments and slow the progression of sarcopenia.

    Original languageEnglish (US)
    Pages (from-to)216-223
    Number of pages8
    JournalExercise and Sport Sciences Reviews
    Volume41
    Issue number4
    DOIs
    StatePublished - Oct 1 2013

    Keywords

    • aging
    • exercise
    • insulin
    • mTORC1
    • muscle protein synthesis
    • protein
    • sarcopenia

    ASJC Scopus subject areas

    • Orthopedics and Sports Medicine
    • Physical Therapy, Sports Therapy and Rehabilitation

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