Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle

Jared M. Dickinson; Elena Volpi; Blake B. Rasmussen

doi:10.1097/JES.0b013e3182a4e699

Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle

Jared M. Dickinson, Elena Volpi, Blake B. Rasmussen

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › peer-review

103 Scopus citations

Abstract

The loss of skeletal muscle size and function with aging and sarcopenia may be related, in part, to an age-related muscle protein synthesis impairment. In this review, we discuss to what extent aging affects skeletal muscle protein synthesis and how nutrition and exercise can be used strategically to overcome age-related protein synthesis impairments and slow the progression of sarcopenia.

Original language	English (US)
Pages (from-to)	216-223
Number of pages	8
Journal	Exercise and Sport Sciences Reviews
Volume	41
Issue number	4
DOIs	https://doi.org/10.1097/JES.0b013e3182a4e699
State	Published - Oct 2013

Keywords

aging
exercise
insulin
mTORC1
muscle protein synthesis
protein
sarcopenia

ASJC Scopus subject areas

Orthopedics and Sports Medicine
Physical Therapy, Sports Therapy and Rehabilitation

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10.1097/JES.0b013e3182a4e699

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Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle

Abstract

Keywords

ASJC Scopus subject areas

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