Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle

Jared M. Dickinson, Elena Volpi, Blake Rasmussen

Research output: Contribution to journalArticle

59 Scopus citations


The loss of skeletal muscle size and function with aging and sarcopenia may be related, in part, to an age-related muscle protein synthesis impairment. In this review, we discuss to what extent aging affects skeletal muscle protein synthesis and how nutrition and exercise can be used strategically to overcome age-related protein synthesis impairments and slow the progression of sarcopenia.

Original languageEnglish (US)
Pages (from-to)216-223
Number of pages8
JournalExercise and Sport Sciences Reviews
Issue number4
StatePublished - Oct 2013



  • aging
  • exercise
  • insulin
  • mTORC1
  • muscle protein synthesis
  • protein
  • sarcopenia

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this