Exploring the potential of variola virus infection of cynomolgus macaques as a model for human smallpox

Keyphrases

• Acute Lethality 33%
• Aerosol 33%
• Antiviral Drugs 33%
• Apoptotic Mechanism 33%
• Bioterrorism 33%
• Bystander 33%
• Cascading Activation 33%
• Cell-Associated 33%
• Coagulation Cascade 33%
• Cynomolgus Macaque 100%
• Cytokine Storm 33%
• D-dimer 33%
• Disease Course 33%
• Disease Pathogenesis 33%
• Disease-specific Mortality 33%
• Electron Microscopy 33%
• Gastrointestinal Tract 33%
• Haemorrhagic Diathesis 33%
• High Dose 33%
• Histologic 33%
• Immunohistochemistry 33%
• Improved Vaccines 33%
• India 33%
• Infected Macrophages 33%
• Inoculation 33%
• Interleukin-6 33%
• Leukocytosis 33%
• Liver 33%
• Low Mortality 33%
• Lymphoid Tissue 66%
• Monocytic Cells 33%
• Multisystem 33%
• Oral mucosa 33%
• Organ Dysfunction 33%
• Plaque-forming Units 33%
• Protective Efficacy 33%
• Reproductive System 33%
• Serum Creatinine Level 33%
• Smallpox 100%
• Smallpox Virus 33%
• Systemic Disease 33%
• T-cell Mediated 33%
• Therapeutic Intervention 33%
• Thrombocytopenia 33%
• Toxemia 33%
• Two-strain 33%
• Variola Virus 100%
• Viral Antigens 33%
• Viral Burden 33%
• Viral Particles 33%
• Viremia 33%
• Virus Infection 100%
• Virus Replication 33%

Immunology and Microbiology

• Creatinine Blood Level 33%
• Cytokine 33%
• Cytokine Storm 33%
• Drug Megadose 33%
• Electron Microscopy 33%
• Gastrointestinal Tract 33%
• Interleukin 6 33%
• Low Drug Dose 33%
• Lymphoid Tissue 66%
• Macaca fascicularis 100%
• Macrophage 33%
• Mouth Mucosa 33%
• Plaque-Forming Unit 33%
• Smallpox 100%
• Smallpox Virus 100%
• T Cell 33%
• Target Tissue 33%
• Viral Disease 100%
• Viral Load 33%
• Viral Replication 33%
• Viremia 33%
• Virus Antigen 33%
• Virus Particle 33%