Needed is an analytical human factors evaluation framework or tool that would provide empirical metrics for the design of habitable environments and for the optimal functioning of the human crews who must live and work in such environments. Standards that result from this effort could be merged with the database products related to the Man-Systems Integration Standards (MSIS)* managed at NASA-JSC. Whereas the JSC-managed work focuses on the human-technology interface (i.e., humanmachine, human-equipment, human-material interfaces), this framework is interested in two other human factors interfaces. The humanenvironment interface focuses on the interiors and exteriors of the living and working environments in or near space platforms. The human-human interface focuses on the psychosocial aspects of group functioning that optimize mission objectives (as well as those that detract from them).