@article{42f5959a572a497bb0fa60f048eb69a8,
title = "Fabrication of nanoscale bioarrays for the study of cytoskeletal protein binding interactions using nanoimprint lithography",
abstract = "The authors describe a high-throughput patterning process used to create arrays of molecular-scale features for the study of cytoskeletal protein binding interactions. The process uses a shadow-evaporated metal mask to facilitate lift-off of features defined by nanoimprint lithography. This simple and robust approach alleviates difficulties in pattern transfer of ultrasmall features and results in arrays of highly ordered sub-10 nm features which are then functionalized with extracellular matrix proteins. Application of these arrays is demonstrated in cell spreading assays.",
author = "M. Schvartzman and K. Nguyen and M. Palma and J. Abramson and J. Sable and J. Hone and Sheetz, \{M. P.\} and Wind, \{S. J.\}",
note = "Funding Information: This work was supported primarily by the National Science Foundation under Award No. NSF EF-05-07086, as well as by the National Institutes of Health through the NIH Roadmap for Medical Research under Award No. PN2 EY 016586. Additional support from the Nanoscale Science and Engineering Initiative of the National Science Foundation under NSF Award No. CHE-0641523 and by the New York State Office of Science, Technology, and Academic Research (NYSTAR)” is also gratefully acknowledged. The authors are grateful to the Columbia University Center for Electron Transport in Molecular Nanostructures and the Center for Nanostructured Materials for making their processing facilities available for this work.",
year = "2009",
doi = "10.1116/1.3043472",
language = "English (US)",
volume = "27",
pages = "61--65",
journal = "Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures",
issn = "1071-1023",
publisher = "AVS Science and Technology Society",
number = "1",
}