Facile and convenient syntheses of 6,11-dihydro-5H-indeno[1,2-c] isoquinolin-5-ones and 6,11-dihydro-5H-indolo[3,2-c]isoquinolin-5-one

Prakash G. Jagtap, Erkan Baloglu, Garry Southan, William Williams, Aloka Roy, Alexander Nivorozhkin, Nelson Landrau, Kevin Desisto, Andrew L. Salzman, Csaba Szabo

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Abstract

(Chemical Equation Presented) The synthesis of 6,11-dihydro-5H-indeno[1,2- c]isoquinolin-5-ones from the base-promoted condensation reaction of homophthalic anhydride and 2-(bromomethyl)-benzonitrile and a convenient method for the synthesis of indolo[3,2-c]isoquinolinones are described.

Original languageEnglish (US)
Pages (from-to)1753-1756
Number of pages4
JournalOrganic Letters
Volume7
Issue number9
DOIs
StatePublished - Apr 28 2005
Externally publishedYes

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ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Jagtap, P. G., Baloglu, E., Southan, G., Williams, W., Roy, A., Nivorozhkin, A., Landrau, N., Desisto, K., Salzman, A. L., & Szabo, C. (2005). Facile and convenient syntheses of 6,11-dihydro-5H-indeno[1,2-c] isoquinolin-5-ones and 6,11-dihydro-5H-indolo[3,2-c]isoquinolin-5-one. Organic Letters, 7(9), 1753-1756. https://doi.org/10.1021/ol050331m