Familial cases of boutonneuse fever

G. Tringali, S. Mansueto, G. Barba, C. Occhino, E. Farinelila, G. Vitale, David Walker

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Pairs of cases of Boutonneuse Fever (BF) occurred in three families. The illness appeared almost simultaneously in both members of each family, but was generally more serious in one as judged by clinical and laboratory parameters. The possibility of a abed rickettsiosis ≫, that is reactivation of rickettsiae by the blood meal obtained from the first individual by the same tick which fed upon the second individual, could be excluded in two of the three pairs of cases. In only one of the case pairs were the individuals sharing the same bed. The differences in severity of symptoms may be related to the different immunological pattern observed in these patients. Previous rickettsial infection may have provided partial immune protection, as is repeatedly reported in the literature. In one couple, the more seriously ill patient had antibodies of the IgM class, suggesting that this was his first exposure to Rickettsia conorii. The less severely ill patient had antibodies of the IgG class only, presumably as the result of re-exposure after previous asymptomatic infection with spotted-fever-group rickettsia.

Original languageEnglish (US)
Pages (from-to)414-418
Number of pages5
JournalEuropean Journal of Epidemiology
Volume3
Issue number4
DOIs
StatePublished - Dec 1987
Externally publishedYes

Fingerprint

Boutonneuse Fever
Rickettsia
Immunoglobulin Isotypes
Rickettsia conorii
Asymptomatic Infections
Ticks
Immunoglobulin M
Meals
Fever
Immunoglobulin G
Infection

Keywords

  • Boutonneuse fever
  • Familiarity
  • Symptoms

ASJC Scopus subject areas

  • Epidemiology

Cite this

Tringali, G., Mansueto, S., Barba, G., Occhino, C., Farinelila, E., Vitale, G., & Walker, D. (1987). Familial cases of boutonneuse fever. European Journal of Epidemiology, 3(4), 414-418. https://doi.org/10.1007/BF00145654

Familial cases of boutonneuse fever. / Tringali, G.; Mansueto, S.; Barba, G.; Occhino, C.; Farinelila, E.; Vitale, G.; Walker, David.

In: European Journal of Epidemiology, Vol. 3, No. 4, 12.1987, p. 414-418.

Research output: Contribution to journalArticle

Tringali, G, Mansueto, S, Barba, G, Occhino, C, Farinelila, E, Vitale, G & Walker, D 1987, 'Familial cases of boutonneuse fever', European Journal of Epidemiology, vol. 3, no. 4, pp. 414-418. https://doi.org/10.1007/BF00145654
Tringali G, Mansueto S, Barba G, Occhino C, Farinelila E, Vitale G et al. Familial cases of boutonneuse fever. European Journal of Epidemiology. 1987 Dec;3(4):414-418. https://doi.org/10.1007/BF00145654
Tringali, G. ; Mansueto, S. ; Barba, G. ; Occhino, C. ; Farinelila, E. ; Vitale, G. ; Walker, David. / Familial cases of boutonneuse fever. In: European Journal of Epidemiology. 1987 ; Vol. 3, No. 4. pp. 414-418.
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