Familial exercise-induced anaphylaxis

J. A. Grant, J. Farnam, R. A. Lord, D. O. Thueson, M. A. Lett-Brown, H. Wallfisch, D. P. Fine, F. C. Schmalstieg

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


An 18-year-old Hispanic male, his two brothers, father, two paternal uncles, and paternal grandfather experienced cutaneous and cardiorespiratory symptoms during vigorous exercise beginning at about 10 years of age. The propositus was challenged by running to exhaustion and by immersion in hot water. In neither case were allergic signs or symptoms noted; however, plasma histamine rose from undetectable levels to 1.0 and 3.7 ng/ml, respectively. Furthermore, C2 and C5 were significantly reduced and fell during exercise.

Original languageEnglish (US)
Pages (from-to)35-38
Number of pages4
JournalAnnals of Allergy
Issue number1
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy


Dive into the research topics of 'Familial exercise-induced anaphylaxis'. Together they form a unique fingerprint.

Cite this