Fat Preference

a novel model of eating behavior in rats

James Kasper, Sarah B. Johnson, Jonathan Hommel

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Obesity is a growing problem in the United States of America, with more than a third of the population classified as obese. One factor contributing to this multifactorial disorder is the consumption of a high fat diet, a behavior that has been shown to increase both caloric intake and body fat content. However, the elements regulating preference for high fat food over other foods remain understudied. To overcome this deficit, a model to quickly and easily test changes in the preference for dietary fat was developed. The Fat Preference model presents rats with a series of choices between foods with differing fat content. Like humans, rats have a natural bias toward consuming high fat food, making the rat model ideal for translational studies. Changes in preference can be ascribed to the effect of either genetic differences or pharmacological interventions. This model allows for the exploration of determinates of fat preference and screening pharmacotherapeutic agents that influence acquisition of obesity.

Original languageEnglish (US)
Pages (from-to)e51575
JournalJournal of visualized experiments : JoVE
Issue number88
DOIs
StatePublished - 2014

Fingerprint

Feeding Behavior
Oils and fats
Rats
Fats
Food
Obesity
Dietary Fats
High Fat Diet
Energy Intake
Adipose Tissue
Nutrition
Pharmacology
Screening
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fat Preference : a novel model of eating behavior in rats. / Kasper, James; Johnson, Sarah B.; Hommel, Jonathan.

In: Journal of visualized experiments : JoVE, No. 88, 2014, p. e51575.

Research output: Contribution to journalArticle

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