Fatal group A streptococcal meningitis and toxic shock-like syndrome: Case report

Gareth P. Jevon, W. Michael Dunne, Hal K. Hawkins, Dawna L. Armstrong, James M. Musser

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA2) that has recently been associated with widespread toxic shock-like syndrome.

Original languageEnglish (US)
Pages (from-to)91-93
Number of pages3
JournalClinical Infectious Diseases
Volume18
Issue number1
StatePublished - Jan 1994
Externally publishedYes

Fingerprint

Septic Shock
Meningitis
Streptococcus
Autopsy
Clone Cells
Streptococcus pyogenes SpeA protein

ASJC Scopus subject areas

  • Immunology

Cite this

Jevon, G. P., Dunne, W. M., Hawkins, H. K., Armstrong, D. L., & Musser, J. M. (1994). Fatal group A streptococcal meningitis and toxic shock-like syndrome: Case report. Clinical Infectious Diseases, 18(1), 91-93.

Fatal group A streptococcal meningitis and toxic shock-like syndrome : Case report. / Jevon, Gareth P.; Dunne, W. Michael; Hawkins, Hal K.; Armstrong, Dawna L.; Musser, James M.

In: Clinical Infectious Diseases, Vol. 18, No. 1, 01.1994, p. 91-93.

Research output: Contribution to journalArticle

Jevon, GP, Dunne, WM, Hawkins, HK, Armstrong, DL & Musser, JM 1994, 'Fatal group A streptococcal meningitis and toxic shock-like syndrome: Case report', Clinical Infectious Diseases, vol. 18, no. 1, pp. 91-93.
Jevon GP, Dunne WM, Hawkins HK, Armstrong DL, Musser JM. Fatal group A streptococcal meningitis and toxic shock-like syndrome: Case report. Clinical Infectious Diseases. 1994 Jan;18(1):91-93.
Jevon, Gareth P. ; Dunne, W. Michael ; Hawkins, Hal K. ; Armstrong, Dawna L. ; Musser, James M. / Fatal group A streptococcal meningitis and toxic shock-like syndrome : Case report. In: Clinical Infectious Diseases. 1994 ; Vol. 18, No. 1. pp. 91-93.
@article{3e7142ed0a1d41c487febc31bc0b2c16,
title = "Fatal group A streptococcal meningitis and toxic shock-like syndrome: Case report",
abstract = "A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA2) that has recently been associated with widespread toxic shock-like syndrome.",
author = "Jevon, {Gareth P.} and Dunne, {W. Michael} and Hawkins, {Hal K.} and Armstrong, {Dawna L.} and Musser, {James M.}",
year = "1994",
month = "1",
language = "English (US)",
volume = "18",
pages = "91--93",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "1",

}

TY - JOUR

T1 - Fatal group A streptococcal meningitis and toxic shock-like syndrome

T2 - Case report

AU - Jevon, Gareth P.

AU - Dunne, W. Michael

AU - Hawkins, Hal K.

AU - Armstrong, Dawna L.

AU - Musser, James M.

PY - 1994/1

Y1 - 1994/1

N2 - A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA2) that has recently been associated with widespread toxic shock-like syndrome.

AB - A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA2) that has recently been associated with widespread toxic shock-like syndrome.

UR - http://www.scopus.com/inward/record.url?scp=0027955487&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027955487&partnerID=8YFLogxK

M3 - Article

C2 - 8054439

AN - SCOPUS:0027955487

VL - 18

SP - 91

EP - 93

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

IS - 1

ER -