Fatal group a streptococcal meningitis and toxic shock-like syndrome: Case report

Gareth P. Jevon; W. Michael Dunne; Hal K. Hawkins; Dawna L. Armstrong; James M. Musser

doi:10.1093/clinids/18.1.91

Fatal group a streptococcal meningitis and toxic shock-like syndrome: Case report

Gareth P. Jevon, W. Michael Dunne, Hal K. Hawkins, Dawna L. Armstrong, James M. Musser

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28 Scopus citations

Abstract

A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA2) that has recently been associated with widespread toxic shock-like syndrome.

Original language	English (US)
Pages (from-to)	91-93
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	18
Issue number	1
DOIs	https://doi.org/10.1093/clinids/18.1.91
State	Published - Jan 1994
Externally published	Yes

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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abstract = "A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA2) that has recently been associated with widespread toxic shock-like syndrome.",

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AB - A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA2) that has recently been associated with widespread toxic shock-like syndrome.

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Fatal group a streptococcal meningitis and toxic shock-like syndrome: Case report

Abstract

ASJC Scopus subject areas

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