Fatal neonatal echovirus 6 infection: Autopsy case report and review of the literature

K. C. Ventura, H. Hawkins, M. B. Smith, D. H. Walker

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


A full-term, healthy male neonate was delivered by caesarian section to a 26-year-old primigravida woman who had a history of fever and upper respiratory tract infection. On the fourth day of life, the neonate developed a sepsis-like syndrome, acute respiratory and renal failure, and disseminated intravascular coagulopathy. He died 13 days after birth. Postmortem examination revealed jaundice, anasarca, massive hepatic necrosis, adrenal hemorrhagic necrosis, renal medullary hemorrhage, hemorrhagic noninflammatory pneumonia, and severe encephalomalacia. Echovirus type 6 was isolated from blood, liver, and lungs. Although uncommon, echovirus type 6 infection may produce a spectrum of pathologic findings similar to those seen with the more commonly virulent echovirus type 11.

Original languageEnglish (US)
Pages (from-to)85-90
Number of pages6
JournalModern Pathology
Issue number2
StatePublished - 2001


  • Echovirus 6
  • Hepatoadrenal necrosis
  • Neonatal infection

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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