Fatal rocky mountain spotted fever in a 2-year-old child

David Walker, Christopher D. Paddock

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 2-year-old boy developed an acute undifferentiated febrile disease that was considered clinically to be a nonspecific viral syndrome. Progressive deterioration with severe central nervous system involvement, cerebral edema, and brain stem herniation led to death 8 days after onset. Disseminated rickettsial infection of endothelium was accompanied by a lymphohistiocytic vasculitis that is usually the hallmark microscopic lesion recognized by the pathologist. The diagnosis was established by immunohistochemical demonstration of intraendothelial spotted fever group rickettsiae.

Original languageEnglish
Pages (from-to)238-241
Number of pages4
JournalPathology Case Reviews
Volume16
Issue number6
DOIs
StatePublished - Nov 2011

Fingerprint

Rocky Mountain Spotted Fever
Fever
Rickettsia
Brain Edema
Vasculitis
Brain Stem
Endothelium
Central Nervous System
Infection

Keywords

  • Rickettsiae
  • Rocky Mountain spotted fever
  • vasculitis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Fatal rocky mountain spotted fever in a 2-year-old child. / Walker, David; Paddock, Christopher D.

In: Pathology Case Reviews, Vol. 16, No. 6, 11.2011, p. 238-241.

Research output: Contribution to journalArticle

Walker, David ; Paddock, Christopher D. / Fatal rocky mountain spotted fever in a 2-year-old child. In: Pathology Case Reviews. 2011 ; Vol. 16, No. 6. pp. 238-241.
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