Fc-Dependent Polyclonal Antibodies and Antibodies to Outer Membrane Proteins A and B, but Not to Lipopolysaccharide, Protect SCID Mice against Fatal Rickettsia conorii Infection

Medicine & Life Sciences

• Anti-Bacterial Agents 3%
• Anti-Idiotypic Antibodies 4%
• Antibodies 31%
• Antigens 3%
• B-Lymphocyte Epitopes 7%
• Boutonneuse Fever 93%
• Cellular Immunity 5%
• Digestion 5%
• Epitopes 4%
• IgA receptor 74%
• Immune Sera 10%
• Immunity 9%
• Immunoblotting 5%
• Immunoglobulin Fab Fragments 14%
• Infections 8%
• Kinetics 4%
• Lethal Dose 50 19%
• Lipopolysaccharides 48%
• Liver 2%
• Macrophages 3%
• Monoclonal Antibodies 12%
• OMPA outer membrane proteins 90%
• Rickettsia 15%
• Rickettsia conorii 56%
• Rickettsia Infections 8%
• Rickettsia rOmpA 12%
• Serum 2%
• Severe Combined Immunodeficiency 72%
• Spleen 4%
• Spotted Fever Group Rickettsiosis 8%
• Subunit Vaccines 6%

Agriculture & Biology

• animal models 4%
• antibiotics 4%
• antibodies 37%
• antigens 4%
• antiserum 9%
• B-lymphocytes 5%
• blood serum 4%
• cell aggregates 5%
• cell-mediated immunity 6%
• death 4%
• digestion 4%
• epitopes 10%
• fever 5%
• immunity 9%
• immunoblotting 5%
• infection 29%
• kinetics 3%
• lethal dose 50 17%
• lipopolysaccharides 54%
• liver 3%
• macrophages 5%
• mice 32%
• monoclonal antibodies 15%
• organisms 3%
• outer membrane proteins 65%
• polyclonal antibodies 59%
• Rickettsia 7%
• Rickettsia conorii 93%
• severe combined immunodeficiency 100%
• spleen 4%
• subunit vaccines 7%