Fertility preservation in the male: From childhood to adulthood

P. Masson, J. A. Gerber, R. E. Brannigan

Research output: Contribution to journalReview article

Abstract

Approximately 50% of males will develop cancer during their lifetime. In the past, oncologic therapies have largely been focused primarily on cure of the underlying malignancy. With improvements in both diagnostic modalities and treatments, pediatric and adult cancer patients are routinely surviving their disease. For this large group of patients, survivorship issues have become a major concern. Central among these survivorship issues is fertility. For males diagnosed with a malignancy, impaired reproductive potential is often noted even before any cancer therapy has been initiated. Furthermore, cancer treatments, in the form of chemotherapy, radiation therapy, and surgery, can all have potentially deleterious and lasting effects on male reproductive capability. For these reasons, a change in oncologic treatment paradigms has occurred. Now, the offer of fertility preservation to males diagnosed with cancer is a key component of comprehensive oncologic care.

Original languageEnglish (US)
Pages (from-to)461-475
Number of pages15
JournalMinerva Ginecologica
Volume64
Issue number6
StatePublished - Dec 2012

Keywords

  • Fertility
  • Fertility preservation
  • Male infertility
  • Survival rate

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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