Fertilization increases the polyphosphoinositide content of sea urchin eggs

Paul R. Turner; Michael P. Sheetz; Laurinda A. Jaffe

doi:10.1038/310414a0

Fertilization increases the polyphosphoinositide content of sea urchin eggs

Paul R. Turner, Michael P. Sheetz, Laurinda A. Jaffe

Research output: Contribution to journal › Article › peer-review

173 Scopus citations

Abstract

Fertilization of the sea urchin egg stimulates a wave of exocytosis of cortical vesicles^1,2, but the mechanism by which fertilization regulates this secretion is not fully understood. We describe here experiments which suggest that polyphosphoinositide metabolism could be a factor in this regulation. We find that the cortical vesicle exocytosis in the egg of Strongylocentrotus purpuratus is preceded by a 40% increase in its content of triphosphoinositide (TPI) and a 22% increase of diphosphoinositide (DPI).

Original language	English (US)
Pages (from-to)	414-415
Number of pages	2
Journal	Nature
Volume	310
Issue number	5976
DOIs	https://doi.org/10.1038/310414a0
State	Published - 1984
Externally published	Yes

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title = "Fertilization increases the polyphosphoinositide content of sea urchin eggs",

abstract = "Fertilization of the sea urchin egg stimulates a wave of exocytosis of cortical vesicles1,2, but the mechanism by which fertilization regulates this secretion is not fully understood. We describe here experiments which suggest that polyphosphoinositide metabolism could be a factor in this regulation. We find that the cortical vesicle exocytosis in the egg of Strongylocentrotus purpuratus is preceded by a 40% increase in its content of triphosphoinositide (TPI) and a 22% increase of diphosphoinositide (DPI).",

author = "Turner, {Paul R.} and Sheetz, {Michael P.} and Jaffe, {Laurinda A.}",

year = "1984",

doi = "10.1038/310414a0",

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AU - Turner, Paul R.

AU - Sheetz, Michael P.

AU - Jaffe, Laurinda A.

PY - 1984

Y1 - 1984

N2 - Fertilization of the sea urchin egg stimulates a wave of exocytosis of cortical vesicles1,2, but the mechanism by which fertilization regulates this secretion is not fully understood. We describe here experiments which suggest that polyphosphoinositide metabolism could be a factor in this regulation. We find that the cortical vesicle exocytosis in the egg of Strongylocentrotus purpuratus is preceded by a 40% increase in its content of triphosphoinositide (TPI) and a 22% increase of diphosphoinositide (DPI).

AB - Fertilization of the sea urchin egg stimulates a wave of exocytosis of cortical vesicles1,2, but the mechanism by which fertilization regulates this secretion is not fully understood. We describe here experiments which suggest that polyphosphoinositide metabolism could be a factor in this regulation. We find that the cortical vesicle exocytosis in the egg of Strongylocentrotus purpuratus is preceded by a 40% increase in its content of triphosphoinositide (TPI) and a 22% increase of diphosphoinositide (DPI).

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Fertilization increases the polyphosphoinositide content of sea urchin eggs

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