Fertilization increases the polyphosphoinositide content of sea urchin eggs

Paul R. Turner, Michael P. Sheetz, Laurinda A. Jaffe

Research output: Contribution to journalArticlepeer-review

172 Scopus citations


Fertilization of the sea urchin egg stimulates a wave of exocytosis of cortical vesicles1,2, but the mechanism by which fertilization regulates this secretion is not fully understood. We describe here experiments which suggest that polyphosphoinositide metabolism could be a factor in this regulation. We find that the cortical vesicle exocytosis in the egg of Strongylocentrotus purpuratus is preceded by a 40% increase in its content of triphosphoinositide (TPI) and a 22% increase of diphosphoinositide (DPI).

Original languageEnglish (US)
Pages (from-to)414-415
Number of pages2
Issue number5976
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • General


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