Fertilization increases the polyphosphoinositide content of sea urchin eggs

Paul R. Turner, Michael Sheetz, Laurinda A. Jaffe

Research output: Contribution to journalArticle

154 Citations (Scopus)

Abstract

Fertilization of the sea urchin egg stimulates a wave of exocytosis of cortical vesicles1,2, but the mechanism by which fertilization regulates this secretion is not fully understood. We describe here experiments which suggest that polyphosphoinositide metabolism could be a factor in this regulation. We find that the cortical vesicle exocytosis in the egg of Strongylocentrotus purpuratus is preceded by a 40% increase in its content of triphosphoinositide (TPI) and a 22% increase of diphosphoinositide (DPI).

Original languageEnglish (US)
Pages (from-to)414-415
Number of pages2
JournalNature
Volume310
Issue number5976
DOIs
StatePublished - Dec 1 1984
Externally publishedYes

Fingerprint

Phosphatidylinositol Phosphates
Sea Urchins
Exocytosis
Fertilization
Eggs
Ovum
Strongylocentrotus purpuratus
triphosphoinositide
diphosphoinositides

ASJC Scopus subject areas

  • General

Cite this

Fertilization increases the polyphosphoinositide content of sea urchin eggs. / Turner, Paul R.; Sheetz, Michael; Jaffe, Laurinda A.

In: Nature, Vol. 310, No. 5976, 01.12.1984, p. 414-415.

Research output: Contribution to journalArticle

Turner, Paul R. ; Sheetz, Michael ; Jaffe, Laurinda A. / Fertilization increases the polyphosphoinositide content of sea urchin eggs. In: Nature. 1984 ; Vol. 310, No. 5976. pp. 414-415.
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