Fetal membrane architecture, aging and inflammation in pregnancy and parturition

Ramkumar Menon, Lauren S. Richardson, Martha Lappas

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Preterm birth is the single major cause of infant mortality. Short and long term outcomes for infants are often worse in cases of preterm premature rupture of the fetal membranes (pPROM). Thus, increased knowledge of the structure characteristics of fetal membranes as well as the mechanisms of membrane rupture are essential if we are to develop effective treatment strategies to prevent pPROM. In this review, we focus on the role of inflammation and senescence in fetal membrane biology.

Original languageEnglish (US)
Pages (from-to)40-45
Number of pages6
JournalPlacenta
Volume79
DOIs
StatePublished - Apr 2019

Keywords

  • Fetal membranes
  • Inflammation
  • Senescence
  • Structure

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology
  • Developmental Biology

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