Fetal membrane architecture, aging and inflammation in pregnancy and parturition

    Research output: Contribution to journalReview articlepeer-review

    67 Scopus citations

    Abstract

    Preterm birth is the single major cause of infant mortality. Short and long term outcomes for infants are often worse in cases of preterm premature rupture of the fetal membranes (pPROM). Thus, increased knowledge of the structure characteristics of fetal membranes as well as the mechanisms of membrane rupture are essential if we are to develop effective treatment strategies to prevent pPROM. In this review, we focus on the role of inflammation and senescence in fetal membrane biology.

    Original languageEnglish (US)
    Pages (from-to)40-45
    Number of pages6
    JournalPlacenta
    Volume79
    DOIs
    StatePublished - Apr 2019

    Keywords

    • Fetal membranes
    • Inflammation
    • Senescence
    • Structure

    ASJC Scopus subject areas

    • Reproductive Medicine
    • Obstetrics and Gynecology
    • Developmental Biology

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