Fetal membrane architecture, aging and inflammation in pregnancy and parturition

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Preterm birth is the single major cause of infant mortality. Short and long term outcomes for infants are often worse in cases of preterm premature rupture of the fetal membranes (pPROM). Thus, increased knowledge of the structure characteristics of fetal membranes as well as the mechanisms of membrane rupture are essential if we are to develop effective treatment strategies to prevent pPROM. In this review, we focus on the role of inflammation and senescence in fetal membrane biology.

Original languageEnglish (US)
JournalPlacenta
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Premature Rupture Fetal Membranes
Extraembryonic Membranes
Parturition
Inflammation
Pregnancy
Premature Birth
Infant Mortality
Rupture
Membranes
Therapeutics

Keywords

  • Fetal membranes
  • Inflammation
  • Senescence
  • Structure

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology
  • Developmental Biology

Cite this

Fetal membrane architecture, aging and inflammation in pregnancy and parturition. / Menon, Ramkumar; Richardson, Lauren; Lappas, Martha.

In: Placenta, 01.01.2018.

Research output: Contribution to journalArticle

@article{eb048eed790d497283c13350770fe96d,
title = "Fetal membrane architecture, aging and inflammation in pregnancy and parturition",
abstract = "Preterm birth is the single major cause of infant mortality. Short and long term outcomes for infants are often worse in cases of preterm premature rupture of the fetal membranes (pPROM). Thus, increased knowledge of the structure characteristics of fetal membranes as well as the mechanisms of membrane rupture are essential if we are to develop effective treatment strategies to prevent pPROM. In this review, we focus on the role of inflammation and senescence in fetal membrane biology.",
keywords = "Fetal membranes, Inflammation, Senescence, Structure",
author = "Ramkumar Menon and Lauren Richardson and Martha Lappas",
year = "2018",
month = "1",
day = "1",
doi = "10.1016/j.placenta.2018.11.003",
language = "English (US)",
journal = "Placenta",
issn = "0143-4004",
publisher = "W.B. Saunders Ltd",

}

TY - JOUR

T1 - Fetal membrane architecture, aging and inflammation in pregnancy and parturition

AU - Menon, Ramkumar

AU - Richardson, Lauren

AU - Lappas, Martha

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Preterm birth is the single major cause of infant mortality. Short and long term outcomes for infants are often worse in cases of preterm premature rupture of the fetal membranes (pPROM). Thus, increased knowledge of the structure characteristics of fetal membranes as well as the mechanisms of membrane rupture are essential if we are to develop effective treatment strategies to prevent pPROM. In this review, we focus on the role of inflammation and senescence in fetal membrane biology.

AB - Preterm birth is the single major cause of infant mortality. Short and long term outcomes for infants are often worse in cases of preterm premature rupture of the fetal membranes (pPROM). Thus, increased knowledge of the structure characteristics of fetal membranes as well as the mechanisms of membrane rupture are essential if we are to develop effective treatment strategies to prevent pPROM. In this review, we focus on the role of inflammation and senescence in fetal membrane biology.

KW - Fetal membranes

KW - Inflammation

KW - Senescence

KW - Structure

UR - http://www.scopus.com/inward/record.url?scp=85056650249&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85056650249&partnerID=8YFLogxK

U2 - 10.1016/j.placenta.2018.11.003

DO - 10.1016/j.placenta.2018.11.003

M3 - Article

C2 - 30454905

AN - SCOPUS:85056650249

JO - Placenta

JF - Placenta

SN - 0143-4004

ER -