Filovirus outbreak detection and surveillance: Lessons from bundibugyo

Adam MacNeil, Eileen C. Farnon, Oliver W. Morgan, Philip Gould, Tegan K. Boehmer, David D. Blaney, Petra Wiersma, Jordan W. Tappero, Stuart T. Nichol, Thomas G. Ksiazek, Pierre E. Rollin

Research output: Contribution to journalArticlepeer-review

65 Scopus citations


The first outbreak of Ebola hemorrhagic fever (EHF) due to Bundibugyo ebolavirus occurred in Uganda from August to December 2007. During outbreak response and assessment, we identified 131 EHF cases (44 suspect, 31 probable, and 56 confirmed). Consistent with previous large filovirus outbreaks, a long temporal lag (approximately 3 months) occurred between initial EHF cases and the subsequent identification of Ebola virus and outbreak response, which allowed for prolonged person-to-person transmission of the virus. Although effective control measures for filovirus outbreaks, such as patient isolation and contact tracing, are well established, our observations from the Bundibugyo EHF outbreak demonstrate the need for improved filovirus surveillance, reporting, and diagnostics, in endemic locations in Africa.

Original languageEnglish (US)
Pages (from-to)S761-S767
JournalJournal of Infectious Diseases
Issue numberSUPPL. 3
StatePublished - Nov 1 2011
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Filovirus outbreak detection and surveillance: Lessons from bundibugyo'. Together they form a unique fingerprint.

Cite this