Findings on PET/CT-PET/MR secondary to central and peripheral nervous system infection by SARS-CoV-2

Marylin Acuña Hernández; Walter Efrén Roldán Cubides; David Cardoza Ochoa; Liset Sánchez Orduz; Paola Vallejo Armenta; Rodrigo Hernández Ramírez; Uvi Cancino Ramos

doi:10.1016/j.neuarg.2022.10.003

Findings on PET/CT-PET/MR secondary to central and peripheral nervous system infection by SARS-CoV-2

Marylin Acuña Hernández, Walter Efrén Roldán Cubides, David Cardoza Ochoa, Liset Sánchez Orduz, Paola Vallejo Armenta, Rodrigo Hernández Ramírez, Uvi Cancino Ramos

Research output: Contribution to journal › Review article › peer-review

Abstract

Introduction: SARS-CoV-2 infection worldwide has affected about 232,075,351 people and caused at least 4,752,988 deaths according to WHO data. It has been considered that the organ of predilection for involvement by this infection is the lung, but according to the literature, 36.4% of patients have evidenced CNS involvement and 8.9% of the SNP. Materials and methods: An intentional search of the literature was carried out in different medical databases such as Pubmed, Ovid, BMJ, Clinical Key, ScienceDirect, entering keywords such as COVID-19, brain, SARS-CoV-2 infection, PET/CT, PET/RM encephalopathy, accompanied by Boolean operators such as AND, OR and NOT. Results: To date, numerous case reports, case series, and observational studies have been published using different PET/CT or PET/MRI radiotracers with different findings. Conclusion: PET/CT or PET/MRI with 2-[¹⁸F]FDG or [¹⁸F]FDOPA has shown to be a useful tool to detect and understand the disease process in those patients with SARS-CoV-2 neuro-infection in cases of normal structural images.

Original language	English (US)
Pages (from-to)	254-260
Number of pages	7
Journal	Neurologia Argentina
Volume	15
Issue number	3
DOIs	https://doi.org/10.1016/j.neuarg.2022.10.003
State	Published - Jul 1 2023
Externally published	Yes

Keywords

COVID-19
Infection
Meningoencephalitis
Positron emission tomography computed tomography
SARS-CoV-2

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1016/j.neuarg.2022.10.003

Cite this

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title = "Findings on PET/CT-PET/MR secondary to central and peripheral nervous system infection by SARS-CoV-2",

abstract = "Introduction: SARS-CoV-2 infection worldwide has affected about 232,075,351 people and caused at least 4,752,988 deaths according to WHO data. It has been considered that the organ of predilection for involvement by this infection is the lung, but according to the literature, 36.4% of patients have evidenced CNS involvement and 8.9% of the SNP. Materials and methods: An intentional search of the literature was carried out in different medical databases such as Pubmed, Ovid, BMJ, Clinical Key, ScienceDirect, entering keywords such as COVID-19, brain, SARS-CoV-2 infection, PET/CT, PET/RM encephalopathy, accompanied by Boolean operators such as AND, OR and NOT. Results: To date, numerous case reports, case series, and observational studies have been published using different PET/CT or PET/MRI radiotracers with different findings. Conclusion: PET/CT or PET/MRI with 2-[18F]FDG or [18F]FDOPA has shown to be a useful tool to detect and understand the disease process in those patients with SARS-CoV-2 neuro-infection in cases of normal structural images.",

keywords = "COVID-19, Infection, Meningoencephalitis, Positron emission tomography computed tomography, SARS-CoV-2",

author = "{Acu{\~n}a Hern{\'a}ndez}, Marylin and {Rold{\'a}n Cubides}, {Walter Efr{\'e}n} and {Cardoza Ochoa}, David and {S{\'a}nchez Orduz}, Liset and {Vallejo Armenta}, Paola and {Hern{\'a}ndez Ram{\'i}rez}, Rodrigo and {Cancino Ramos}, Uvi",

note = "Publisher Copyright: {\textcopyright} 2022 Sociedad Neurol{\'o}gica Argentina",

year = "2023",

month = jul,

day = "1",

doi = "10.1016/j.neuarg.2022.10.003",

language = "English (US)",

volume = "15",

pages = "254--260",

journal = "Neurologia Argentina",

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T1 - Findings on PET/CT-PET/MR secondary to central and peripheral nervous system infection by SARS-CoV-2

AU - Acuña Hernández, Marylin

AU - Roldán Cubides, Walter Efrén

AU - Cardoza Ochoa, David

AU - Sánchez Orduz, Liset

AU - Vallejo Armenta, Paola

AU - Hernández Ramírez, Rodrigo

AU - Cancino Ramos, Uvi

PY - 2023/7/1

Y1 - 2023/7/1

N2 - Introduction: SARS-CoV-2 infection worldwide has affected about 232,075,351 people and caused at least 4,752,988 deaths according to WHO data. It has been considered that the organ of predilection for involvement by this infection is the lung, but according to the literature, 36.4% of patients have evidenced CNS involvement and 8.9% of the SNP. Materials and methods: An intentional search of the literature was carried out in different medical databases such as Pubmed, Ovid, BMJ, Clinical Key, ScienceDirect, entering keywords such as COVID-19, brain, SARS-CoV-2 infection, PET/CT, PET/RM encephalopathy, accompanied by Boolean operators such as AND, OR and NOT. Results: To date, numerous case reports, case series, and observational studies have been published using different PET/CT or PET/MRI radiotracers with different findings. Conclusion: PET/CT or PET/MRI with 2-[18F]FDG or [18F]FDOPA has shown to be a useful tool to detect and understand the disease process in those patients with SARS-CoV-2 neuro-infection in cases of normal structural images.

AB - Introduction: SARS-CoV-2 infection worldwide has affected about 232,075,351 people and caused at least 4,752,988 deaths according to WHO data. It has been considered that the organ of predilection for involvement by this infection is the lung, but according to the literature, 36.4% of patients have evidenced CNS involvement and 8.9% of the SNP. Materials and methods: An intentional search of the literature was carried out in different medical databases such as Pubmed, Ovid, BMJ, Clinical Key, ScienceDirect, entering keywords such as COVID-19, brain, SARS-CoV-2 infection, PET/CT, PET/RM encephalopathy, accompanied by Boolean operators such as AND, OR and NOT. Results: To date, numerous case reports, case series, and observational studies have been published using different PET/CT or PET/MRI radiotracers with different findings. Conclusion: PET/CT or PET/MRI with 2-[18F]FDG or [18F]FDOPA has shown to be a useful tool to detect and understand the disease process in those patients with SARS-CoV-2 neuro-infection in cases of normal structural images.

KW - COVID-19

KW - Infection

KW - Meningoencephalitis

KW - Positron emission tomography computed tomography

KW - SARS-CoV-2

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Findings on PET/CT-PET/MR secondary to central and peripheral nervous system infection by SARS-CoV-2

Abstract

Keywords

ASJC Scopus subject areas

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