TY - JOUR
T1 - Fine needle aspiration of an intrathyroidal parathyroid carcinoma mimicking a primary thyroid anaplastic carcinoma
T2 - A case report with review of the literature
AU - Mir, Fatima
AU - Rohra, Prih
AU - Aakash, Nfn
AU - Furlan, Karina
AU - Ghai, Ritu
AU - Reddy, Vijaya
AU - Cheng, Lin
AU - Gattuso, Paolo
N1 - Publisher Copyright:
© 2020 Wiley Periodicals LLC
PY - 2021/1
Y1 - 2021/1
N2 - Intrathyroidal parathyroid carcinoma is an uncommon malignancy. A 46-year-old male presented with a left neck mass. Computed tomography (CT) scan revealed a hypodense mass in the left thyroid lobe along with evidence of metastatic lymphadenopathy. Aspiration of the left thyroid nodule was performed, and a diagnosis of malignancy was rendered, favoring a primary anaplastic carcinoma. Based on the cytologic diagnosis, the patient underwent a total thyroidectomy. Before the surgery, intact parathyroid hormone (PTH) and calcium level (PTH = 78 pg/mL; Calcium = 10.6 mg/dL) were found to be minimally elevated. On gross examination, a 3.2 cm mass within the left inferior thyroid lobe was seen. Histopathologic examination and ancillary studies supported the diagnosis of a parathyroid carcinoma. We, hereby present, an exceedingly rare presentation of an intrathyroidal parathyroid carcinoma with only minimal elevation of PTH and calcium, mimicking a primary anaplastic thyroid carcinoma on cytologic examination.
AB - Intrathyroidal parathyroid carcinoma is an uncommon malignancy. A 46-year-old male presented with a left neck mass. Computed tomography (CT) scan revealed a hypodense mass in the left thyroid lobe along with evidence of metastatic lymphadenopathy. Aspiration of the left thyroid nodule was performed, and a diagnosis of malignancy was rendered, favoring a primary anaplastic carcinoma. Based on the cytologic diagnosis, the patient underwent a total thyroidectomy. Before the surgery, intact parathyroid hormone (PTH) and calcium level (PTH = 78 pg/mL; Calcium = 10.6 mg/dL) were found to be minimally elevated. On gross examination, a 3.2 cm mass within the left inferior thyroid lobe was seen. Histopathologic examination and ancillary studies supported the diagnosis of a parathyroid carcinoma. We, hereby present, an exceedingly rare presentation of an intrathyroidal parathyroid carcinoma with only minimal elevation of PTH and calcium, mimicking a primary anaplastic thyroid carcinoma on cytologic examination.
KW - fine needle aspiration parathyroid
KW - intrathyroidal parathyroid carcinoma
KW - intrathyroidal parathyroid lesions
KW - parathyroid cytology
UR - http://www.scopus.com/inward/record.url?scp=85088962987&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85088962987&partnerID=8YFLogxK
U2 - 10.1002/dc.24560
DO - 10.1002/dc.24560
M3 - Article
C2 - 32749783
AN - SCOPUS:85088962987
SN - 8755-1039
VL - 49
SP - E14-E19
JO - Diagnostic cytopathology
JF - Diagnostic cytopathology
IS - 1
ER -