First experience using contrast-enhanced ultrasound to evaluate vascularisation of acellular dermal matrices after implant-based breast reconstruction

Daryousch Parvizi, Franz Haas, Florentia Peintinger, Martin Hubmer, Thomas Rappl, Horst Koch, Michael Schintler, Stephan Spendel, Lars Peter Kamolz, Paul Wurzer, Alexandru Tuca, Michael Fuchsjaeger, Roland Weinke

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Acellular dermal matrices (ADM) have been used frequently in therapeutic and prophylactic breast procedures. To date there have been no reports on vascularisation of ADMs and formation of tissue around them as seen with modern non-invasive imaging techniques such as contrast-enhanced ultrasound (CEUS). In this case series, we used CEUS to investigate the features of ADM in relation to vascular ingrowth and scaffold for "new" tissue formation. This is a retrospective evaluation of patients who underwent successful skin- and nipple-sparing mastectomy (SSM, NSM) with immediate IBBR using ADM from May 31, 2010, through December 28, 2012. Over a 24-month period, 16 patients, with an average age of 44 years (range 27-70 years), were evaluated with CEUS. No contrast agent allergies or side effects were reported for the ultrasound examination. After contrast agent injection (1-18 months postoperatively), homogeneous normal enhancement in the ADM and peripheral region with physiological tissue formation was seen in all patients. In this small study, the most obvious contribution of CEUS is the in vivo evaluation of vascular ingrowth and tissue formation after IBBR with ADM after follow-up of 1-18 months postoperatively. Level of Evidence III: Retrospective cohort or comparative study; case-control study; or systematic review of these studies.

Original languageEnglish (US)
Pages (from-to)461-467
Number of pages7
JournalBreast Journal
Volume20
Issue number5
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Acellular Dermis
Mammaplasty
Contrast Media
Blood Vessels
Tissue Scaffolds
Nipples
Mastectomy
Case-Control Studies
Hypersensitivity
Breast
Skin
Injections

Keywords

  • ADM
  • Breast reconstruction
  • CEUS
  • IBBR
  • Mastectomy
  • NSM
  • SSM

ASJC Scopus subject areas

  • Internal Medicine
  • Oncology
  • Surgery
  • Medicine(all)

Cite this

First experience using contrast-enhanced ultrasound to evaluate vascularisation of acellular dermal matrices after implant-based breast reconstruction. / Parvizi, Daryousch; Haas, Franz; Peintinger, Florentia; Hubmer, Martin; Rappl, Thomas; Koch, Horst; Schintler, Michael; Spendel, Stephan; Kamolz, Lars Peter; Wurzer, Paul; Tuca, Alexandru; Fuchsjaeger, Michael; Weinke, Roland.

In: Breast Journal, Vol. 20, No. 5, 2014, p. 461-467.

Research output: Contribution to journalArticle

Parvizi, D, Haas, F, Peintinger, F, Hubmer, M, Rappl, T, Koch, H, Schintler, M, Spendel, S, Kamolz, LP, Wurzer, P, Tuca, A, Fuchsjaeger, M & Weinke, R 2014, 'First experience using contrast-enhanced ultrasound to evaluate vascularisation of acellular dermal matrices after implant-based breast reconstruction', Breast Journal, vol. 20, no. 5, pp. 461-467. https://doi.org/10.1111/tbj.12301
Parvizi, Daryousch ; Haas, Franz ; Peintinger, Florentia ; Hubmer, Martin ; Rappl, Thomas ; Koch, Horst ; Schintler, Michael ; Spendel, Stephan ; Kamolz, Lars Peter ; Wurzer, Paul ; Tuca, Alexandru ; Fuchsjaeger, Michael ; Weinke, Roland. / First experience using contrast-enhanced ultrasound to evaluate vascularisation of acellular dermal matrices after implant-based breast reconstruction. In: Breast Journal. 2014 ; Vol. 20, No. 5. pp. 461-467.
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